Trial · NCT05377203
Low-dose Quadruple Combination Therapy in Patients With Hypertension
NCT05377203, Phase 4, Completed, The Third Xiangya Hospital of Central South University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Low-dose Quadruple Combination Therapy in Patients With Hypertension. Trials, record NCT05377203. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05377203
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Low-dose Quadruple Combination Therapy in Patients With Hypertension
- NCT number
- NCT05377203
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 90 participants, actual
- Lead sponsor
- The Third Xiangya Hospital of Central South University
- Conditions
- Hypertension, Arterial Hypertension
- Interventions
- Quadruple combination of half doses therapy→Dual combination of standard dose therapy, Dual combination of standard dose therapy→ Quadruple combination of half doses therapy
- First posted
- 2022-05-17
- Last updated
- 2023-07-18
Source ClinicalTrials.gov
Registered outcomes22
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Mean systolic blood pressure of 24-hour | Four weeks | The reduction of mean systolic blood pressure of 24-hour in Ambulatory Blood Pressure Monitoring (ABPM) after 4 weeks of medication (from baseline). |
| Secondary | Mean systolic blood pressure of daytime and night | Four weeks | The reduction of mean systolic blood pressure of daytime and night in ABPM after 4 weeks of medication (from baseline). |
| Secondary | Mean diastolic blood pressure of 24-hour, daytime and night | Four weeks | The reduction of mean diastolic blood pressure of 24-hour, daytime and night in ABPM after 4 weeks of medication (from baseline). |
| Secondary | Morning blood pressure surge | Four weeks | The change of morning blood pressure surge in ABPM after 4 weeks of medication (from baseline). |
| Secondary | Office blood pressure | Four weeks | The reduction of office blood pressure after 4 weeks of medication (from baseline). |
| Secondary | Home blood pressure | Four weeks | The reduction of home blood pressure after 4 weeks of medication (from baseline). |
| Secondary | Heart rate | Four weeks | The change in heart rate after 4 weeks of medication (from baseline). |
| Secondary | Controlled rate of blood pressure | Four weeks | Controlled rate of blood pressure after 4 weeks of medication (from baseline). |
| Other | Percentage of participants with severe adverse events (SAE) | Four weeks | Percentage of participants with any SAE according to Good Clinical Practice definition. |
| Other | Percentage of participants with side effects | Four weeks | Percentage of participants with occurrence of any potentially relevant side effect (pre-specified as in study protocol). |
1 to 10 of 22Source ClinicalTrials.gov
See all 22 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers9
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05377203
GET https://conductscience.org/api/trials/v1/NCT05377203/registered?page=2