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Trial · NCT05455684

Results by group48

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline to Day 43 in the Montgomery-Asberg Depression Rating Scale (MADRS) Total ScorePlacebo-11.4Standard Error 0.98Units on a scale
Change From Baseline to Day 43 in the Montgomery-Asberg Depression Rating Scale (MADRS) Total ScoreAticaprant 10 mg-12.3Standard Error 0.95Units on a scale
Change From Baseline to Day 43 in Dimensional Anhedonia Rating Scale (DARS) Total ScorePlacebo10.5Standard Error 1.50Units on a scale
Change From Baseline to Day 43 in Dimensional Anhedonia Rating Scale (DARS) Total ScoreAticaprant 10 mg12.0Standard Error 1.43Units on a scale
Change From Baseline Over Time in MADRS Total ScorePlaceboAt Day 15-5.4Standard Error 0.76Units on a scale
Change From Baseline Over Time in MADRS Total ScoreAticaprant 10 mgAt Day 15-6.6Standard Error 0.72Units on a scale
Change From Baseline Over Time in MADRS Total ScorePlaceboAt Day 29-9.4Standard Error 0.90Units on a scale
Change From Baseline Over Time in MADRS Total ScoreAticaprant 10 mgAt Day 29-11.1Standard Error 0.87Units on a scale
Change From Baseline Over Time in MADRS Total ScorePlaceboAt Day 43-11.4Standard Error 0.98Units on a scale
Change From Baseline Over Time in MADRS Total ScoreAticaprant 10 mgAt Day 43-12.3Standard Error 0.95Units on a scale
Percentage of Participants Who Achieved Response on Depressive Symptoms Scale Based on MADRS Total Score at Day 43Placebo22.8Percentage of participants
Percentage of Participants Who Achieved Response on Depressive Symptoms Scale Based on MADRS Total Score at Day 43Aticaprant 10 mg29.4Percentage of participants
Percentage of Participants With Remission of Depressive Symptoms Based on MADRS Total Score at Day 43Placebo12.6Percentage of participants
Percentage of Participants With Remission of Depressive Symptoms Based on MADRS Total Score at Day 43Aticaprant 10 mg17.6Percentage of participants
Change From Baseline to Day 43 in Patient Health Questionnaire, 9-Item (PHQ-9) Total ScorePlacebo-5.9Standard Error 0.58Units on a scale
Change From Baseline to Day 43 in Patient Health Questionnaire, 9-Item (PHQ-9) Total ScoreAticaprant 10 mg-6.7Standard Error 0.55Units on a scale
Change From Baseline Over Time in DARS Total ScorePlaceboAt Day 154.8Standard Error 1.22Units on a scale
Change From Baseline Over Time in DARS Total ScoreAticaprant 10 mgAt Day 155.9Standard Error 1.20Units on a scale
Change From Baseline Over Time in DARS Total ScorePlaceboAt Day 298.3Standard Error 1.38Units on a scale
Change From Baseline Over Time in DARS Total ScoreAticaprant 10 mgAt Day 2910.0Standard Error 1.32Units on a scale

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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