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Trial · NCT05507476

Nasal Desmopressin Versus Topical Epinephrine in Endonasal Dacryocystorhinostomy

NCT05507476, Not applicable, Completed, Zagazig University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Nasal Desmopressin Versus Topical Epinephrine in Endonasal Dacryocystorhinostomy. Trials, record NCT05507476. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05507476

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Nasal Desmopressin Versus Topical Epinephrine in Endonasal Dacryocystorhinostomy
NCT number
NCT05507476
Status
Completed
Phases
Not applicable
Enrollment
52 participants, actual
Lead sponsor
Zagazig University
Conditions
Anesthesia
Interventions
Desmopressin Acetate Nasal, 10 μg/0.1 ml per spray, Epinephrine topical 1:100,000 Nasal Packs
First posted
2022-08-19
Last updated
2024-10-01

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryIntraoperative blood lossMeasurement will be done at the 30th minutes of the start of surgery.Estimation of intraoperative blood loss will be done at 30th minutes of surgery. by calculating the loss of blood and irrigation saline in 50 mL-graded suction canisters.
PrimaryIntraoperative blood lossMeasurement will be done at 60th minutes of the start of surgery.Estimation of intraoperative blood loss will be done at 60th minutes of surgery. by calculating the loss of blood and irrigation saline in 50 mL-graded suction canisters.
SecondaryThe Surgical field clarityat the end of surgery
The quality of surgical field based on BOEZAART grading system(0 no bleeding; 1 slight bleeding: no suctioning is needed; 2 slight bleeding: occasional suctioning needed;, 3 sight bleeding: frequent suctioning required, bleeding threatens surgical field a few seconds after suction is removed; 4 moderate bleeding: frequent suctioning required and bleeding threatens surgical field directly after suction is removed; 5 severe bleeding: constant suctioning required)
SecondaryChange in heart rate (HR) in beat per minutewill be recorded at 2 minutes, 5 minutes, 10 minutes, 30 minutes and 60 minutes after topical epinephrine packs insertion.Change in heart rate (HR) from baseline.
SecondaryChange mean arterial blood pressure (MAP) in mmHgwill be recorded at 2 minutes, 5 minutes, 10 minutes, 30 minutes and 60 minutes after topical epinephrine packs insertion.Change mean arterial blood pressure (MAP) from baseline.
SecondaryChange oxygen saturation (SPO2)will be recorded at 2 minutes, 5 minutes, 10 minutes, 30 minutes and 60 minutes after topical epinephrine packs insertion.Change oxygen saturation (SPO2) from baseline.
SecondaryChange in serum sodium levelpreoperative and after 12 hours postoperativeSerum sodium level will be measured pre \& postoperative to detect and manage any sodium disturbances.
SecondaryThe surgeon's satisfactionAt the end of surgeryThe surgeon was asked to rate satisfaction at the end of surgery (4 =excellent, 3 = good, 2 = fair, 1 = poor, 0 = extremely poor).

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers6

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
7614641BACKGROUNDPubMed
25895497BACKGROUNDPubMed
25919247BACKGROUNDPubMed
26152362BACKGROUNDPubMed
31161361BACKGROUNDPubMed
34318721BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05507476

GET https://conductscience.org/api/trials/v1/NCT05507476/registered