Effect of Cognitive Training on Gait in Parkinson's Disease
NCT05514379, Not applicable, Unknown, General University Hospital, Prague
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effect of Cognitive Training on Gait in Parkinson's Disease | ClinicalTrials.gov |
| NCT number | NCT05514379 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 50 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | General University Hospital, Prague | ClinicalTrials.gov |
| Conditions | Parkinson Disease | ClinicalTrials.gov |
| Interventions | cognitive training | ClinicalTrials.gov |
| First posted | 2022-08-24 | ClinicalTrials.gov |
| Last updated | 2023-09-14 | ClinicalTrials.gov |
Registered outcomes 35
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change from Baseline instrumental assessment of turn fluency during rapid turns at 12 weeks | Baseline and 12 weeks | see Bertoli et al. 2019 for a detailed description; G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Primary | Change from Baseline Timed Up and Go Test: dual-task performance at 12 weeks | Baseline and 12 weeks | Patient is asked to perform TUG while subtracting 3 from a random number between 51-100; G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Secondary | Timed Up and Go Test: single-task performance | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Secondary | 10-meter walking test: single-task performance | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Secondary | 10-meter walking test: dual-task performance | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Patient is asked to perform 10MWT while subtracting 3 from a random number between 51-100; G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Secondary | Number of steps/day | 5 days monitoring at baseline and 12 weeks | Assessed using Fitbit activity trackers | ClinicalTrials.gov |
| Secondary | The Montreal Cognitive Assessment (MoCA), Total score | Baseline, 12 weeks, 3 months follow-up | Global cognition screening | ClinicalTrials.gov |
| Secondary | Trail Making Test A (TMT A), Total score (in seconds) | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Assessing of attention distribution. | ClinicalTrials.gov |
| Secondary | The Victoria Version of Stroop Test (VST): Dot Time Score (in seconds) Neutral Word Time Score (in seconds) The Victoria Version of Stroop Test (VST): Dot Time Score (in seconds) Neutral Word Time Score (in seconds) | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Assessing of focused visual attention | ClinicalTrials.gov |
| Secondary | The Victoria Version of Stroop Test (VST): Color Word Time Score (in seconds) Error score on VST Color Word Task, Total score | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Assessing of executive functions - inhibition | ClinicalTrials.gov |
| Secondary | Tower of London, Total score | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Assessing of executive functions - problem solving | ClinicalTrials.gov |
| Secondary | Depression, Anxiety and Stress Scale (DASS 21) | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Self-assessment scale of depression, anxiety and stress. Patient fills it at home. | ClinicalTrials.gov |
| Secondary | Falls Efficacy Scale-International | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Fear of falls assessment | ClinicalTrials.gov |
| Secondary | Number of falls | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Diary based quantification of the number of falls | ClinicalTrials.gov |
| Secondary | Change from post-intervention instrumental assessment of turn fluency during rapid turns at 1 month follow-up | 12 weeks and 1 month follow-up | see Bertoli et al. 2019 for a detailed description; G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Secondary | Change from post-intervention instrumental assessment of turn fluency during rapid turns at 3 months follow-up | 12 weeks and 3 months follow-up | see Bertoli et al. 2019 for a detailed description; G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Secondary | Change from post-intervention Timed Up and Go Test: dual-task performance at 1 month follow-up | 12 weeks and 1 month follow-up | Patient is asked to perform TUG while subtracting 3 from a random number between 51-100; G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Secondary | Change from post-intervention Timed Up and Go Test: dual-task performance at 3 months follow-up | 12 weeks and 3 months follow-up | Patient is asked to perform TUG while subtracting 3 from a random number between 51-100; G-Walk instrumental gait assessment will be used | ClinicalTrials.gov |
| Other | Counting: number of (correct) answers per second | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Patient is asked to subtract 3 from a random number between 51-100 while seated. This assessment is used as a reference value for TUG-DT and 10MWT-DT | ClinicalTrials.gov |
| Other | MDS-Unified Parkinson's Disease Rating Scale | Baseline, 12 weeks, 1 month follow-up, 3 months follow-up | Scale evaluating various aspects of Parkinson's disease including non-motor and motor experiences of daily living and motor complications. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 9
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 8
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Category Fluency | Other outcome | ConductCognition |
| Digit Span Test | Other outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Tower Planning | Secondary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
| Trail Making Test B | Other outcome | ConductCognition |
| Verbal Fluency | Other outcome | ConductCognition |
| Verbal Learning | Other outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)