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Trial · NCT05519046

Cardiac Contractility Modulation in Chagas Heart Disease

NCT05519046, Not applicable, Recruiting, InCor Heart Institute

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Cardiac Contractility Modulation in Chagas Heart Disease. Trials, record NCT05519046. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05519046

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Cardiac Contractility Modulation in Chagas Heart Disease
NCT number
NCT05519046
Status
Recruiting
Phases
Not applicable
Enrollment
60 participants, estimated
Lead sponsor
InCor Heart Institute
Conditions
Chagas Cardiomyopathy, Heart Failure, Systolic Dysfunction, Right Bundle Branch Block and Left Anterior Fascicular Block, Right Bundle Branch Block and Left Posterior Fascicular Block
Interventions
Cardiac Contractility Modulation (CCM), CRT
First posted
2022-08-29
Last updated
2026-07-08

Source ClinicalTrials.gov

Registered outcomes11

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryQoL ScoreAt baselineKCCQS - Kansas City cardiomyopathy quality score
PrimaryQoL ScoreAt 6 monthsKCCQS - Kansas City cardiomyopathy quality score
PrimaryGLSAt baselineGlobal longitudinal strain at rest/effort - (tissue tracking)
PrimaryGLSAt 6 monthsGlobal longitudinal strain at rest/effort - (tissue tracking)
Secondary6MWTAt baseline6-minute walk test
Secondary6MWTAt 6 months6-minute walk test
SecondaryNYHAFCAt baselineHF functional class assessed as established by the NYHA
SecondaryNYHAFCAt 6 monthsHF functional class assessed as established by the NYHA
SecondaryLVEFAt baselineLeft ventricle ejection fraction
SecondaryLVEFAt 6 monthsLeft ventricle ejection fraction

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers32

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
2365530RESULTPubMed
2486527RESULTPubMed
3997291RESULTPubMed
4982469RESULTPubMed
4994717RESULTPubMed
7055867RESULTPubMed
7547025RESULTPubMed
7987526RESULTPubMed
7994859RESULTPubMed
8175216RESULTPubMed

1 to 10 of 32

See all 32 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05519046

GET https://conductscience.org/api/trials/v1/NCT05519046/papers?page=2