Trial · NCT05543681
Clinical Trial on Agitation in Alzheimer's Dementia
NCT05543681, Phase 2, Active not recruiting, IGC Pharma, LLC
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Clinical Trial on Agitation in Alzheimer's Dementia. Trials, record NCT05543681. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05543681
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Clinical Trial on Agitation in Alzheimer's Dementia
- NCT number
- NCT05543681
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 164 participants, estimated
- Lead sponsor
- IGC Pharma, LLC
- Conditions
- Alzheimer Disease, Agitation,Psychomotor, Care Giving Burden, NPS, Aggression
- Interventions
- IGC-AD1-Active, IGC-AD1-Placebo
- First posted
- 2022-09-16
- Last updated
- 2026-09-30
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Agitation | Baseline to week six | Change in mean Cohen Mansfield Agitation Inventory (CMAI) score |
| Secondary | Acute Agitation | Baseline to week two | Change in mean Cohen Mansfield Agitation Inventory (CMAI) score |
| Other | Agitation at week four | Baseline to week four | Change in mean Cohen Mansfield Agitation Inventory (CMAI) score |
| Other | Participant overall wellbeing | Baseline to weeks two and six | Change in the Clinical Global Impression Scale (CGI) |
| Other | Participant executive functions | Baseline to week six | Change in Mini-Mental State Examination (MMSE2) score |
| Other | Depression | Baseline to weeks two, four, and six | Change in mean Cornell Scale for Depression in Dementia (CSDD) score |
| Other | Neuropsychiatric symptoms | Baseline to weeks two, four, and six | Change in mean Neuropsychiatric Inventory (NPI-12) score |
| Other | Participant quality of life | Baseline to weeks two, four and six | Change in mean Quality of Life in Alzheimer's Disease (QOL-AD) score |
| Other | Caregiver burden | Baseline to weeks two and six | Change in mean Zarit Burden Interview (ZBI) score |
| Other | Psychotropic drugs | Baseline to six weeks | Change in type and dosage of psychotropic drugs |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05543681
GET https://conductscience.org/api/trials/v1/NCT05543681/registered