Trial · NCT05551858
Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis
NCT05551858, Phase 1, Phase 2, Active not recruiting, Georgetown University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis. Trials, record NCT05551858. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05551858
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis
- NCT number
- NCT05551858
- Status
- Active not recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 32 participants, estimated
- Lead sponsor
- Georgetown University
- Conditions
- Safety Issues, Pain, Pancreas Fibrosis
- Interventions
- Proglumide, Placebo
- First posted
- 2022-09-23
- Last updated
- 2026-08-05
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in blood chemistry tests | 12 weeks of therapy | Number of participants with abnormal chemistry blood tests at 12-weeks in placebo arm compared to treatment arm |
| Primary | Adverse events | 12 weeks of therapy | Number of Adverse events according to the Common Toxicity criteria Version 5.0 occurring in proglumide-treated compared to placebo-treated groups |
| Secondary | Change in Pain Measurements from baseline to end of treatment with proglumide compared to Placebo | Baseline mean scores on a scale of 1 to 5 will be compared to scores at 12 weeks and 24 weeks | Change in Pain score from baseline using the Patient-Reported Outcomes Measurement Information System (PROMIS Item Bank v1.1 - Pain Interference scale 1-5). |
| Secondary | Change in Pain Measurements numeric score from baseline to end of treatment with proglumide compared to Placebo | Baseline mean scores compared to scores at 12 weeks and 24 weeks | Change in mean pain scores on a scale of 0 to 10 at baseline to end of treatment using the Numeric Pain Scale (ranking of intensity of pain over 24 hr scored with a number from 0 or no pain to 10- severe pain. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05551858
GET https://conductscience.org/api/trials/v1/NCT05551858/registered