Trial · NCT05570305
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 11 of 11
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change from baseline in albuminuria after 4 weeks combined zibotentan and dapagliflozin treatment versus four weeks treatment with zibotentan alone. | The albuminuria will be measured before start of medication intake and after the last intake of medication for each treatment period. This concerns a 4 week time frame. | The change in albuminuria as expressed the percentage change of the log-transformed albumin:creatinine ratio in mg/gram. The log-transformation is because of the skewed distribution. |
| Secondary | Change in Extracellular Fluid | 4 weeks | Extracellular Fluid measured by bioimpedance spectroscopy |
| Secondary | Change in bodyweight | 4 weeks | Change in kilograms |
| Secondary | Change in NT-proBNP | 4 weeks | N-terminal B-type natriuretic peptide (NT-proBNP) |
| Secondary | Change in BNP | 4 weeks | B-type natriuretic peptide (BNP) |
| Secondary | Change in Glomerular Filtration Rate (GFR) | 4 weeks | Glomerular Filtration Rate (GFR) using iohexol clearance techniques. |
| Secondary | Change in Extracellular volume (ECV) | 4 weeks | Extracellular volume (ECV) using iohexol clearance techniques. |
| Secondary | Change in hematocrit | 4 weeks | The percentage of red blood cells in blood |
| Secondary | Change in systolic and diastolic blood pressure | 4 weeks | Change in blood pressure as measure in mmHg |
| Other | Change in renin-angiotensin-aldosterone system (RAAS) markers | 4 weeks | Change in RAAS markers in plasma and urine |
| Other | Change in copeptin | 4 weeks | Change in copeptin as a surrogate of vasopressin |
Source ClinicalTrials.govtrials-2026-11-12-0.4.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT05570305/registered