Trial · NCT05584007
Cellulitis Optimal Antibiotic Treatment
NCT05584007, Phase 3, Recruiting, University of Southampton
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cellulitis Optimal Antibiotic Treatment. Trials, record NCT05584007. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05584007
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cellulitis Optimal Antibiotic Treatment
- NCT number
- NCT05584007
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 334 participants, estimated
- Lead sponsor
- University of Southampton
- Conditions
- Cellulitis of Leg
- Interventions
- Flucloxacillin Only Product in Oral Dose Form, Placebo Only Product in Oral Dose Form
- First posted
- 2022-10-18
- Last updated
- 2026-05-15
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pain assessment | Days 7-16 | Self-reported pain (measured using the Pain Numeric Rating Scale (0-10)) |
| Secondary | Use of additional antibiotics | Up to day 28 | Any reported use of antibiotics other than the initial 5 days of flucloxacillin and 2 days of IMP) |
| Secondary | Patient-reported assessment of how well they are feeling | Days 6-14 | Numeric rating scale NRS (0-10) and assessed as repeated measures |
| Secondary | Health related quality of life | Days 6-14 | EQ-5D-5L - values, and individual dimension (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) level scores using repeated measures. |
| Secondary | Health related quality of life used to estimate Quality Adjusted- Life Years (QALYs) | Days 6-14 | EQ-5D-5L - values, and individual dimension (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) level scores using repeated measures. |
| Secondary | Leg swelling and warmth | Day 7, 14, 21, 28 | Participant reported questionnaire |
| Secondary | Time until self-reported recovery | Day 7, 14, 21, 28 | Participant reported questionnaire |
| Secondary | Time until self-assessed extent of cellulitis starts to reduce (with no subsequent increase) | Day 7, 14, 21, 28 | Participant reported questionnaire |
| Secondary | Hospital admissions | 12 months | Number of hosptial admissions since randomisation, collected from primary care notes review |
| Secondary | Recurrent cellulitis episodes over 12 months (number of episodes) | 12 months | Recurrent cellulitis episodes over 12 months (number of episodes) since randomisation, collected from primary care notes review |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05584007
GET https://conductscience.org/api/trials/v1/NCT05584007/registered