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Trial · NCT05584605

Perfusion Augmentation Through Exercise

NCT05584605, Not applicable, Unknown, University of Zurich

3 sourcestrials-2026-11-12-0.4.0

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ConductScience Library. Perfusion Augmentation Through Exercise. Trials, record NCT05584605. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05584605

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Perfusion Augmentation Through Exercise
NCT number
NCT05584605
Status
Unknown
Phases
Not applicable
Enrollment
40 participants, estimated
Lead sponsor
University of Zurich
Conditions
Stroke, Ischemic
Interventions
Aerobic treadmill training, Stretching exercise
First posted
2022-10-18
Last updated
2022-10-18

Source ClinicalTrials.gov

Registered outcomes18

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryBrain imaging - cerebrovascular reactivity (CVR) by BOLD-fMRIpost-intervention (12 weeks)
Functional brain tissue perfusion and tissue at risk based on cerebrovascular reactivity by blood oxygenation-level dependent functional magnetic resonance imaging (BOLD-fMRI), measured as the percentage BOLD signal change /mmHg CO2.
SecondaryBrain imaging - intravoxel incoherent motion (IVIM)post-intervention (12 weeks)Functionality of brain microvasculature by measuring diffusion and perfusion components of tissue based on intravoxel incoherent motion
SecondaryBrain imaging - NOVA-qMRIpost-intervention (12 weeks)Blood flow velocity based on non-invasive optimal vessel analysis quantitative magnetic resonance imaging
SecondaryBrain imaging - Lesion volumepost-intervention (12 weeks)based on 3D T1 weighted imaging, 3D Fluid-Attenuated Inversion Recovery (FLAIR), Diffusion-Eighted Imaging (DWI)
SecondaryBrain imaging - Collateral statuspost-intervention (12 weeks)Collateral status based on 3D time of flight angiography (TOF)
SecondaryExercise stress testingpost-intervention (12 weeks)Cycle ergometer testing with spirometry
SecondarySix-Minute Walk Test (6MWT)post-intervention (12 weeks) + follow-up (+3 months)Functional walking capacity in meters
SecondaryTen-Meter Walk Test (10MWT)post-intervention (12 weeks) + follow-up (+3 months)Walking speed in m/s
SecondaryFugl-Meyer Assessment of the Lower Extremity (FMMA-LE)post-intervention (12 weeks) + follow-up (+3 months)Stroke-specific motor impairment index to assess lower limb motor function with a total score ranging from 0 to 34 and higher scores indicating better performance.
SecondaryMotricity Index of the Lower Extremity (MI-LE)post-intervention (12 weeks) + follow-up (+3 months)Muscle strength assessment of three major muscle groups of the lower extremity with a total score ranging from 0 to 100 and higher scores indicating better performance.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests4

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
Corsi Block-Tapping TestSecondary outcomeConductCognition
Digit Span TestSecondary outcomeConductCognition
Stroop Color-Word TestSecondary outcomeConductCognition
Verbal LearningSecondary outcomeConductCognition

Source

Release
trials-2026-11-12-0.4.0
Release manifest SHA-256
0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
Registry capture
2026-11-12
Results copy, AACT
2026-03-23
NIH clinical studies file
2026-11-13

Source ClinicalTrials.gov

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05584605

GET https://conductscience.org/api/trials/v1/NCT05584605/registered