Trial · NCT05602467
Long Term Transcranial Pulse Stimulation (TPS) on Older Adults With Mild Neurocognitive Disorder (NCD)
NCT05602467, Not applicable, Unknown, The University of Hong Kong
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Long Term Transcranial Pulse Stimulation (TPS) on Older Adults With Mild Neurocognitive Disorder (NCD). Trials, record NCT05602467. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05602467
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Long Term Transcranial Pulse Stimulation (TPS) on Older Adults With Mild Neurocognitive Disorder (NCD)
- NCT number
- NCT05602467
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 22 participants, estimated
- Lead sponsor
- The University of Hong Kong
- Conditions
- Mild Neurocognitive Disorder
- Interventions
- Transcranial Pulse Stimulation (TPS), Treatment as usual (TAU)
- First posted
- 2022-11-02
- Last updated
- 2023-07-27
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Global Cognition | Baseline, at 12 weeks, at 24 weeks, 12-week Follow-up | Global cognitive function measured by the Hong Kong Chinese version of the Montreal Cognitive Assessment (HK-MoCA) ranges from 0 to 30, with higher scores indicating better cognition. |
| Secondary | Change in Memory | Baseline, at 12 weeks, at 24 weeks, 12-week Follow-up | Measured by Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) - Chinese version |
| Secondary | Change in Executive Function | Baseline, at 12 weeks, at 24 weeks, 12-week Follow-up | Measured by Stroop test. |
| Secondary | Change in Attention/Working Memory | Baseline, at 12 weeks, at 24 weeks, 12-week Follow-up | Measured by Trail Making Test Parts A and B |
| Secondary | Change in Brain Structure | Baseline, 12-week Follow-up | Structural MRI will be performed using a 3T scanner at HKU. Pre and post intervention brain MRI scan will be used during intervention and evaluate the changes in brain structure. The participants' brain images will be loaded into the TPS machine before the session start. Those participants with abnormal brain scan result such as brain tumour and recent stroke will be excluded. Images processing and analysis will be performed using software packages including FSL and SPM8 to assess the voxel-based morphometry (VBM) in hippocampus and other relevant regions. |
| Secondary | Change in Daily Functioning | Baseline, at 12 weeks, at 24 weeks, 12-week Follow-up | Measured by Hong Kong Chinese version of the Lawton Instrumental Activities of Daily Living Scale. |
| Secondary | Change in Mood | Baseline, at 12 weeks, at 24 weeks, 12-week Follow-up | Measured by the Depression Rating Scale (HAMD-17) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers21
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests3
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
| Trail Making Test B | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05602467
GET https://conductscience.org/api/trials/v1/NCT05602467/papers?page=2