Trial · NCT05604794
A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health
NCT05604794, Phase 4, Completed, Field Trip Health; results first posted 2023-05-12
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health. Trials, record NCT05604794. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05604794
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health
- NCT number
- NCT05604794
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 1,806 participants, actual
- Lead sponsor
- Field Trip Health
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder
- Interventions
- Ketamine-Assisted Psychotherapy (KAP)
- First posted
- 2022-11-03
- Last updated
- 2024-03-20
- Results first posted
- 2023-05-12
- Limitations and caveats
- Based on feedback from the peer review process, this study should be considered a cohort study rather than a trial. The high attrition rate may limit validity of results.
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 9-item Patient Health Questionnaire (PHQ-9) | Change from 3 months compared to baseline | Self-reported measure of depression, ranging from 0-27. Higher scores are worse. |
| Primary | 7-item Generalized Anxiety Disorder Measure (GAD-7) | Change from 3 months compared to baseline | Self-reported measure of anxiety, ranging from 0-21. Higher scores are worse. |
| Primary | 6-item PTSD Checklist (PCL-6) | Change from 3 months compared to baseline | Self-reported measure of post traumatic stress, ranging from 6-30. Higher scores are worse. |
| Secondary | 9-item Patient Health Questionnaire (PHQ-9) | Change from 1 month compared to baseline | Self-reported measure of depression, ranging from 0-27. |
| Secondary | 9-item Patient Health Questionnaire (PHQ-9) | Change from 6 months compared to baseline | Self-reported measure of depression, ranging from 0-27. |
| Secondary | 7-item Generalized Anxiety Disorder Measure (GAD-7) | Change from 1 month compared to baseline | Self-reported measure of anxiety, ranging from 0-21. |
| Secondary | 7-item Generalized Anxiety Disorder Measure (GAD-7) | Change from 6 months compared to baseline | Self-reported measure of anxiety, ranging from 0-21. |
| Secondary | 6-item PTSD Checklist (PCL-6) | Change from 1 month compared to baseline | Self-reported measure of post traumatic stress, ranging from 6-30. |
| Secondary | 6-item PTSD Checklist (PCL-6) | Change from 6 months compared to baseline | Self-reported measure of post traumatic stress, ranging from 6-30. |
Source ClinicalTrials.gov
Outcomes9
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | 9-item Patient Health Questionnaire (PHQ-9) | Change from 3 months compared to baseline | Number analysed after attrition. | units on a scale | MEAN |
| PRIMARY | 7-item Generalized Anxiety Disorder Measure (GAD-7) | Change from 3 months compared to baseline | Number analysed after attrition. | units on a scale | MEAN |
| PRIMARY | 6-item PTSD Checklist (PCL-6) | Change from 3 months compared to baseline | Number analysed after attrition. | units on a scale | MEAN |
| SECONDARY | 9-item Patient Health Questionnaire (PHQ-9) | Change from 1 month compared to baseline | units on a scale | MEAN | |
| SECONDARY | 9-item Patient Health Questionnaire (PHQ-9) | Change from 6 months compared to baseline | units on a scale | MEAN | |
| SECONDARY | 7-item Generalized Anxiety Disorder Measure (GAD-7) | Change from 1 month compared to baseline | units on a scale | MEAN | |
| SECONDARY | 7-item Generalized Anxiety Disorder Measure (GAD-7) | Change from 6 months compared to baseline | units on a scale | MEAN | |
| SECONDARY | 6-item PTSD Checklist (PCL-6) | Change from 1 month compared to baseline | units on a scale | MEAN | |
| SECONDARY | 6-item PTSD Checklist (PCL-6) | Change from 6 months compared to baseline | units on a scale | MEAN |
Source ClinicalTrials.gov
Results by group9
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| 9-item Patient Health Questionnaire (PHQ-9) | Clients | -3.23 | 95% Confidence Interval -3.57 to -2.90 | units on a scale | |
| 7-item Generalized Anxiety Disorder Measure (GAD-7) | Clients | -4.80 | 95% Confidence Interval -5.17 to -4.44 | units on a scale | |
| 6-item PTSD Checklist (PCL-6) | Clients | -4.24 | 95% Confidence Interval -4.60 to -3.87 | units on a scale | |
| 9-item Patient Health Questionnaire (PHQ-9) | Clients | -3.23 | 95% Confidence Interval -3.57 to -2.90 | units on a scale | |
| 9-item Patient Health Questionnaire (PHQ-9) | Clients | -4.74 | 95% Confidence Interval -5.68 to -3.80 | units on a scale | |
| 7-item Generalized Anxiety Disorder Measure (GAD-7) | Clients | -2.65 | 95% Confidence Interval -2.95 to -2.34 | units on a scale | |
| 7-item Generalized Anxiety Disorder Measure (GAD-7) | Clients | -4.10 | 95% Confidence Interval -5.02 to -3.18 | units on a scale | |
| 6-item PTSD Checklist (PCL-6) | Clients | -2.14 | 95% Confidence Interval -2.44 to -1.83 | units on a scale | |
| 6-item PTSD Checklist (PCL-6) | Clients | -3.44 | 95% Confidence Interval -4.38 to -2.50 | units on a scale |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Clients | 1,806 | |
| Overall Study | COMPLETED | Clients | 94 | |
| Overall Study | NOT COMPLETED | Clients | 1,712 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Clients | 0 | 1,806 |
| Total, other adverse events | Clients | 0 | 1,806 |
| Total, serious adverse events | Clients | 0 | 1,806 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05604794
GET https://conductscience.org/api/trials/v1/NCT05604794/registered