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Trial · NCT05611268

Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger Syndrome

NCT05611268, Not applicable, Unknown, University of Sao Paulo General Hospital

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger Syndrome. Trials, record NCT05611268. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05611268

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger Syndrome
NCT number
NCT05611268
Status
Unknown
Phases
Not applicable
Enrollment
48 participants, estimated
Lead sponsor
University of Sao Paulo General Hospital
Conditions
Eisenmenger Syndrome
Interventions
Pentoxifylline
First posted
2022-11-10
Last updated
2023-12-15

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPlasma concentration of Thrombomodulin3 months and 6 monthsChange in plasma concentration of thrombomoduin at 3 months and 6 months of pentoxifylline therapy compared to baseline.
SecondaryPlasma concentration of tissue factor3 months and 6 monthsChange in plasma concentration of tissue factor at 3 months and 6 months of pentoxifylline therapy compared to baseline.
SecondaryMonocyte thrombomodulin content3 months and 6 monthsChange in mean fluorescence intensity (MFI) for thrombomodulin in circulating (blood) monocytes measured by flow cytometry 3 months and 6 months of pentoxifylline therapy compared to baseline.
SecondaryMonocyte tissue factor content3 months and 6 monthsChange in mean fluorescence intensity (MFI) for tissue factor in circulating (blood) monocytes measured by flow cytometry 3 months and 6 months of pentoxifylline therapy compared to baseline.
SecondaryPlasma concentration of other markers of thrombosis3 months and 6 monthsChange in plasma concentration of D-dimer and thrombin-antithrombin complexes at 3 months and 6 months of pentoxifylline therapy compared to baseline.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05611268

GET https://conductscience.org/api/trials/v1/NCT05611268/registered