Trial · NCT05622136
Dose-escalation of Regorafenib in Advanced Hepatocellular Carcinoma
NCT05622136, Phase 2, Active not recruiting, Instituto do Cancer do Estado de São Paulo
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Dose-escalation of Regorafenib in Advanced Hepatocellular Carcinoma. Trials, record NCT05622136. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05622136
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Dose-escalation of Regorafenib in Advanced Hepatocellular Carcinoma
- NCT number
- NCT05622136
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 28 participants, estimated
- Lead sponsor
- Instituto do Cancer do Estado de São Paulo
- Conditions
- Liver Cancer, Hepatocellular Carcinoma
- Interventions
- Regorafenib Oral Product
- First posted
- 2022-11-18
- Last updated
- 2026-03-27
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Proportion of patients who complete 4 cycles of treatment | 4 months | |
| Secondary | Proportion of patients with disease control after 4 treatment cycles; | 4 months | Patients with partial response or stable disease after 4 cycles |
| Secondary | Median overall survival: time from treatment initiation to death; | 5 years | Time from treatment initiation to death |
| Secondary | Median progression-free survival: time from treatment initiation to progression or death | 5 years | Time from treatment initiation to progression or death |
| Secondary | Score in the The 5-level EuroQol EQ-5D-5L questionnaire | 5 years | \- 0.532 (worst health state) and 1 (most optimal health state) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05622136
GET https://conductscience.org/api/trials/v1/NCT05622136/registered