Trial · NCT05628727
Intermittent Fasting Interventions on Brain Health in Women
NCT05628727, Not applicable, Terminated, McMaster University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Intermittent Fasting Interventions on Brain Health in Women. Trials, record NCT05628727. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05628727
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Intermittent Fasting Interventions on Brain Health in Women
- NCT number
- NCT05628727
- Status
- Terminated
- Phases
- Not applicable
- Enrollment
- 6 participants, actual
- Lead sponsor
- McMaster University
- Conditions
- Psychological Stress
- Interventions
- Time Restricted Feeding, 5:2 Fasting
- First posted
- 2022-11-29
- Last updated
- 2025-09-12
Source ClinicalTrials.gov
Registered outcomes22
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Depression, Anxiety and Stress Scale (DASS-21) Questionnaire - Stress Sub-Scale | 8 weeks | Investigators will administer the standardized DASS-21 Questionnaire at Week 0 and Week 8. The stress sub-scale will be used to measure any potential effects of fasting interventions on psychological stress over time. The scoring of answers is based on a 0 to 3 scale. 3 reflects the negative extreme on the Likert Scale. Scores range from 0-42, higher scores are indicative of higher psychological stress levels. |
| Secondary | Colour and Word Stroop Test (SCWT) | 8 weeks | Investigators will administer the standardized SCWT at Week 0 and Week 8 to assess the potential effects of fasting interventions on selective attention and response inhibition in participants over time. This task requires participants to name the displayed colour of the presented words while they disregard the meaning of the words. Several outcome measures will be produced: 1. Reaction time (RT) in milliseconds (ms) 2. The Stroop Effect - the difference in RT between incongruent and congruent trials, which can be broken down into 2 components: 1. Stroop interference effect - the RT difference between incongruent and neutral trials 2. Stroop facilitation effect - the RT difference between the neutral and congruent trials |
| Secondary | Mnemonic Similarity Task (MST) | 8 weeks | Investigators will administer the standardized MST to assess the potential effects of fasting interventions on high interference memory over time. Several outcome measures will be produced: 1. Reaction time 2. High-interference memory (assessed as the ability to correctly identify lure items as ''Similar'') 3. General recognition memory performance (assessed as the ability to correctly identify repetitions items as ''Old'') |
| Secondary | Pittsburgh Sleep Quality Index (PSQI) | 8 weeks | Investigators will administer the standardized PSQI at Week 0 and Week 8 to measure the self-reported quality and patterns of sleep in adults. Several outcomes will be measured: 1. Subjective sleep quality 2. Sleep latency 3. Sleep duration 4. Habitual sleep efficiency 5. Sleep disturbances 6. Use of sleeping medication 7. Daytime dysfunction over the last month The scoring of answers is based on a 0 to 3 scale. 3 reflects the negative extreme on the Likert Scale. Scores range from 0-21, where higher scores are indicative of poorer sleep quality and a global score of \>5 is indicative of poor sleep quality. |
| Secondary | Eating Disorder Examination Questionnaire (EDE-Q 6.0) | 8 weeks | Investigators will administer the standardized EDEQ-6.0 during screening and Week 8 to measure self-reported disordered eating patterns in adults and the potential effects of fasting interventions on this outcome measure over time. 2 main outcomes will be measured: 1. Frequency data on key behavioural features of eating disorders in terms of the number of episodes of the behaviour. 2. Sub-scale scores reflect the severity of characteristics of eating disorders. The sub-scales are Restraint, Eating Concern, Shape Concern and Weight Concern. Generally, sub scales are measures on a 7-point Likert scale. Higher scores on the global scale and sub-scales denote more problematic eating behaviours and attitudes. |
| Secondary | Profile of Mood States (POMS) | 8 weeks | Investigators will administer the standardized POMS at Week 0 and Week 8 to measure the potential effects of fasting interventions on self-reported quality and patterns of sleep in adults over time. Several outcomes will be measured: 1. Total Mood Disturbance \[TMD\] (-32 to 200) Subscales: 2. Anger (0-48) 3. Confusion (0-28) 4. Depression (0-60) 5. Fatigue (0-28) 6. Tension (0-36) 7. Vigour (0-32) The scoring of answers is based on a 5-point Likert scale (not at all - extremely). Higher TMD scores are indicative of a poorer mood state. |
| Secondary | State Anxiety Inventory (STAI) Short Form | 8 weeks | Investigators will administer the standardized STAI at Week 0 and Week 8 to measure the potential effects of fasting interventions on self-reported state and trait anxiety levels over time. All items are rated on a 4-point Likert scale (e.g., from "Almost Never" to "Almost Always"), with higher scores indicating greater anxiety levels. |
| Secondary | Five Facet Mindfulness Questionnaire (FFMQ) | 8 weeks | Investigators will administer the standardized FFMQ at Week 0 and Week 8 to measure the potential effects of fasting interventions on the self-reported trait-like tendency to be mindful in daily life. It is comprised of the following five related facets: observing, describing, acting with awareness, non-judging, and non-reactivity. The 39 items of the FFMQ are rated on a 5-point Likert scale: ranging from 1 (never or very rarely true) to 5 (very often or always true). Facet scores can also be combined to produce an overall mindfulness score. A higher score indicates a greater trait-like tendency to be mindful in daily life. |
| Secondary | Blood Pressure | 8 weeks | Investigators will use an automated sphygmomanometer to measure blood pressure during each of the 2 in-lab sessions. Several measures will be collected: 1. MAP (mmHg) 2. Systolic pressure (mmHg) 3. Diastolic pressure (mmHg) |
| Secondary | Height (cm) | 8 weeks | Investigators will use a vertical scale via measuring tape to measure height (cm) during each of the 2 in-lab sessions. |
1 to 10 of 22Source ClinicalTrials.gov
See all 22 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Mnemonic Similarity Task | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05628727
GET https://conductscience.org/api/trials/v1/NCT05628727/registered?page=2