Lifestyle Interventions for Vitality and Empowerment in Seniors
NCT05631106, Not applicable, Unknown, Wake Forest University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Lifestyle Interventions for Vitality and Empowerment in Seniors | ClinicalTrials.gov |
| NCT number | NCT05631106 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 30 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Wake Forest University | ClinicalTrials.gov |
| Conditions | Cognitive Change | ClinicalTrials.gov |
| Interventions | High Intensity Interval Resistance Training, Stretching, Balance, and Range of motion | ClinicalTrials.gov |
| First posted | 2022-11-30 | ClinicalTrials.gov |
| Last updated | 2022-11-30 | ClinicalTrials.gov |
Registered outcomes 14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Executive Functioning | Baseline and 12-weeks | Executive Functioning will be operationalized as an index of several computer-based tasks assessing aspects of executive functioning: Inhibition (Stroop Test), Updating (The 4-part continuous performance task), and Switching (Shifting attention task, Symbol Digit Coding). | ClinicalTrials.gov |
| Primary | Gradual Continuous Performance Test | Baseline and 12-weeks | Participants will make continuous responses to target picture stimuli (images of cities among distractor images of mountains). Periodically, a colored border will appear around each location, cuing the participant to attend to either the left or right picture stream. If the currently cued stream differs from their previous focus of attention, the participant will make a saccadic eye movement. At the same time as the color onset, a number will appear at each location. Participants will then make an even/odd discrimination for stimuli appearing at the to-be-attended location. | ClinicalTrials.gov |
| Primary | Functional Magnetic Resonance Imagining | Baseline and 12-weeks | Participants will complete a 60-minute magnetic resonance imagining session during which will acquire a high-resolution anatomical scan, an echo planar image while participants complete the Gradual Continuous Performance Test. This task is a cognitive task designed to measure the neural correlates of moment-by-moment fluctuations in the efficacy of sustained attention and attention shifting readiness, termed attentional flexibility, a resting state scan, and a diffusion tensor imaging to measure white matter tract integrity. | ClinicalTrials.gov |
| Secondary | Brain Derived Neurotrophic Factor | Baseline and 12-weeks | Blood will be drawn using venipuncture to collect a serum sample. A blood analysis will be performed to examine brain derived neurotrophic factor, a marker suggesting an increase hippocampal neural growth. | ClinicalTrials.gov |
| Secondary | The Physical Activity Enjoyment Scale | Baseline and 12-weeks | The physical activity enjoyment scale captures the extent to which an individual enjoys the physical activities they are currently participating in. The individual is asked to respond to 18 items with bipolar anchors on a 7-point Likert-type scale (e.g., 1=I enjoy it, 7=I hate it; 1=I feel bored, 7=I feel interested). | ClinicalTrials.gov |
| Secondary | Community Health Activities Model Program for Seniors Activity Questionnaire for Older Adults | Baseline and 12-weeks | This physical activity questionnaire tasks participants with reporting the extent to which they participated in various occupational, transport, leisure time, and home physical activities in the previous 4 weeks (e.g., "In a typical or normal week during the past 4 weeks, did you do heavy gardening?"). If the participant indicates "yes" they next indicate the weekly frequency and duration of the activity. Following scoring, the scale produces variables capturing average weekly frequency, duration, and caloric expenditure for both total physical activity and exercise-specific activities. | ClinicalTrials.gov |
| Secondary | Basic Psychological Need Satisfaction and Frustration Scales | Baseline and 12-weeks | he BPNSFS reflect the extent to which an individual experiences satisfaction and frustration in achieving the core human needs of relatedness, competence, and autonomy. Participants respond to 24 questions (e.g., "I feel a sense of choice and freedom in the things I undertake") on a 5-point Likert-type scale where 1 indicates "Not True at All" and 5 indicates "Completely True". The scale produces 6 subscale scores, including both frustration and satisfaction subscales for autonomy, competence, and satisfaction. Each subscale is computed as the sum of four questionnaire items, with scores ranging from 4-20, with higher scores reflecting greater satisfaction or frustration. | ClinicalTrials.gov |
| Secondary | SF-36 Health Questionnaire | Baseline and 12-weeks | The SF-36 is a generic measure of health status/health-related quality of life that consists of two norm-based composite T-scales, mental health and physical function, and 8 subscales: physical functioning, mental health, role-physical, role-emotional, bodily pain, general health, vitality, and social functioning. | ClinicalTrials.gov |
| Secondary | 400 Meter Walk Test | Baseline and 12-weeks | The 400 meter walk test assesses walking speed and endurance in older adults on a 20 meter course. The timed walk covers 10 laps totaling 400 meters. | ClinicalTrials.gov |
| Secondary | Short Physical Performance Battery | Baseline and 12-weeks | This measure assesses lower extremity functioning. | ClinicalTrials.gov |
| Secondary | Stroop Test | Baseline and 12-weeks | This is a three part test. Participants will be asked to respond the words "RED", "GREEN", "YELLOW", "BLUE", and "GREEN" in different colors according to the instructions provided for each part. | ClinicalTrials.gov |
| Secondary | Symbol Digit Coding | Baseline and 12-weeks | The symbol digit coding test measures complex information processing accuracy, complex attention, visual-perceptual speed, and information processing speed. | ClinicalTrials.gov |
| Secondary | Four-Part Continuous Performance Test | Baseline and 12-weeks | The four-part continuous performance is a test that measures the participant's working memory and sustained attention. | ClinicalTrials.gov |
| Secondary | Shifting Attention Test | Baseline and 12-weeks | The shifting attention test is a measure of ability to shift from one instruction set to another quickly and accurately. Participants will be instructed to match geometric objects either by shape or by color. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Continuous Performance Test | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)