Trial · NCT05637606
HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery
NCT05637606, Not applicable, Completed, Humanitas Clinical and Research Center
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery. Trials, record NCT05637606. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05637606
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery
- NCT number
- NCT05637606
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 636 participants, actual
- Lead sponsor
- Humanitas Clinical and Research Center
- Conditions
- Blood Pressure, Complication,Postoperative, Intraoperative Hypotension
- Interventions
- Ephedrine, Norepinephrine, Etilefrine Hydrochloride bolus, Use of pulse pressure and stroke volume variation (PPV and SVV); use of Mini Fluid Challenge (mini_FC)
- First posted
- 2022-12-05
- Last updated
- 2025-06-11
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Composite endpoint of postoperative mortality and at least one major organ dysfunction (see description in the secondary outcomes). | up to 30 days after operation | Composite postoperative outcome |
| Secondary | Hospital stay (days) | up to 30 days after operation | Hospital stay (days) |
| Secondary | ICU stay (days) | up to 30 days after operation | Intensive Care Unit stay (days) |
| Secondary | ICU readmission | up to 30 days after operation | Intensive Care Unit readmissions |
| Secondary | Sequential Organ Failure Assessment (SOFA) scores on postoperative | up to 7 days after operation | Postoperative organ failure - SOFA scores ranges from 0 (\<2% of mortality) to 24 (\>90% of mortality) |
| Secondary | Overall intraoperative fluid balance | day 1 after the operation | Intraoperative infusions (crystalloids, colloids, blood products) / Intraoperative loss balance (urine output) |
| Secondary | Mortality | up to 30 days after operation | Mortality |
| Secondary | Vasopressors use | day 1 after the operation | Dose and timing of vasoactive drug infusion intraoperatively |
| Secondary | Need for reoperation | day 30 after operation | Need of a new surgical treatment |
| Other | CARDIOVASCULAR complications | day 7 after operation | * Acute heart failure * Myocardial injury after non-cardiac surgery * Myocardial infarction * Bradycardia * Symptomatic proximal deep venous thrombosis * Peripheral arterial and venous thrombosis |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05637606
GET https://conductscience.org/api/trials/v1/NCT05637606/registered