Trial · NCT05661227
Mechanism of Cardiac and Cerebral Function Injury Caused by Intraoperative Limb Ischemia-reperfusion
NCT05661227, Not applicable, Unknown, Hebei Medical University Third Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Mechanism of Cardiac and Cerebral Function Injury Caused by Intraoperative Limb Ischemia-reperfusion. Trials, record NCT05661227. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05661227
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Mechanism of Cardiac and Cerebral Function Injury Caused by Intraoperative Limb Ischemia-reperfusion
- NCT number
- NCT05661227
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 120 participants, estimated
- Lead sponsor
- Hebei Medical University Third Hospital
- Conditions
- Ischemic Reperfusion Injury
- Interventions
- Dexmedetomidine, 0.9% Sodium chloride, Tourniquet(Early), Tourniquet(Late)
- First posted
- 2022-12-22
- Last updated
- 2022-12-22
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | SOD | Baseline to day2 | Superoxide dismutase |
| Primary | MDA | Baseline to day2 | Malonaldehyde |
| Primary | IL-6 | Baseline to day2 | Interleukin- 6 |
| Primary | TNF-α | Baseline to day2 | Tumor necrosis factor-α |
| Primary | hs-Tn | Baseline to day2 | High sensitive troponin |
| Primary | BDNF | Baseline to day2 | Brain-derived neurotrophic factor |
| Secondary | HRV | Baseline to day2 | HeartRateVariability |
| Secondary | PRR | Baseline to day2 | Pulse Repetition Rate |
| Secondary | BP | Baseline to day2 | Blood Pressure（both systolic and diastolic blood pressure will be measured） |
| Secondary | SpO2 | Baseline to day2 | Peripheral capillary oxygen saturation |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05661227
GET https://conductscience.org/api/trials/v1/NCT05661227/registered