Intensive Blood Pressure Control in Ischaemic Stroke Patients With Severe Cerebral Small Vessel Disease
NCT05690997, Not applicable, Unknown, The University of Hong Kong
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Intensive Blood Pressure Control in Ischaemic Stroke Patients With Severe Cerebral Small Vessel Disease | ClinicalTrials.gov |
| NCT number | NCT05690997 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 104 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | The University of Hong Kong | ClinicalTrials.gov |
| Conditions | Small Vessel Cerebrovascular Disease, Stroke | ClinicalTrials.gov |
| Interventions | Intensive treatment, Standard treatment | ClinicalTrials.gov |
| First posted | 2023-01-19 | ClinicalTrials.gov |
| Last updated | 2023-02-03 | ClinicalTrials.gov |
Registered outcomes 7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Cerebral Blood Flow | From Baseline to approximate 1 year after recruitment | Change in whole-brain CBF as measured using MRI ASL at end of study (1 year) compared to baseline. | ClinicalTrials.gov |
| Secondary | Grey Matter - Cerebral Blood Flow | From Baseline to approximate 1 year after recruitment | Change in Grey Matter CBF as measured using MRI ASL at end of study (1 year) compared to baseline. | ClinicalTrials.gov |
| Secondary | White Matter - Cerebral Blood Flow | From Baseline to approximate 1 year after recruitment | Change in white matter CBF as measured using MRI ASL at end of study (1 year) compared to baseline. | ClinicalTrials.gov |
| Secondary | Structural Connectivity | From Baseline to approximate 1 year after recruitment | Change in structural connectivity CBF as measured using MRI DTI at end of study (1 year) compared to baseline. | ClinicalTrials.gov |
| Secondary | Cognitive Function - MoCA | From Baseline to approximate 1 year after recruitment | Change in MoCA Score at end of study (1 year) | ClinicalTrials.gov |
| Secondary | Cognitive Function - Stroop colour-word test | From Baseline to approximate 1 year after recruitment | Change in Stroop colour-word test Score at end of study (1 year) | ClinicalTrials.gov |
| Secondary | Cognitive Function - Digit Symbol Coding test | From Baseline to approximate 1 year after recruitment | Change in Digital Symbol Coding test Score at end of study (1 year) | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 25
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 1852179 | BACKGROUND | PubMed |
| 3496763 | BACKGROUND | PubMed |
| 10923056 | BACKGROUND | PubMed |
| 15860749 | BACKGROUND | PubMed |
| 17210627 | BACKGROUND | PubMed |
| 19672065 | BACKGROUND | PubMed |
| 21193179 | BACKGROUND | PubMed |
| 23726159 | BACKGROUND | PubMed |
| 24255596 | BACKGROUND | PubMed |
| 24788967 | BACKGROUND | PubMed |
| 25165388 | BACKGROUND | PubMed |
| 28495831 | BACKGROUND | PubMed |
| 28515266 | BACKGROUND | PubMed |
| 29507944 | BACKGROUND | PubMed |
| 29523652 | BACKGROUND | PubMed |
| 29739911 | BACKGROUND | PubMed |
| 29748422 | BACKGROUND | PubMed |
| 29748646 | BACKGROUND | PubMed |
| 29792871 | BACKGROUND | PubMed |
| 29966494 | BACKGROUND | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Symbol Coding | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)