Trial · NCT05704426
Arrythmia Burden in Cardiac Contractility Modulation (CCM)
NCT05704426, Terminated, Hackensack Meridian Health; results first posted 2024-08-19
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Arrythmia Burden in Cardiac Contractility Modulation (CCM). Trials, record NCT05704426. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05704426
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Arrythmia Burden in Cardiac Contractility Modulation (CCM)
- NCT number
- NCT05704426
- Status
- Terminated
- Enrollment
- 2 participants, actual
- Lead sponsor
- Hackensack Meridian Health
- Conditions
- Atrial Fibrillation, Arrythmia
- Interventions
- Impulse Dynamics Optimizer Device
- First posted
- 2023-01-30
- Last updated
- 2024-08-19
- Results first posted
- 2024-08-19
- Limitations and caveats
The study was terminated after only two patients in the retrospective cohort were included. No study activities were conducted for the prospective cohort and there was no formal statistical analysis conducted given the very limited sample size.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Atrial Fibrillation (AF) Burden | 8 months post optimizer implantation | Compare the AF burden noted 6 months pre Optimizer implant to 6 post Optimizer months (post Optimizer months 3-8), after 2 month blanking period |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Atrial Fibrillation (AF) Burden | 8 months post optimizer implantation | AF burden was defined as the average minutes of AF/day. Outcome is reported at the pre implantation (pre-ccm) and at 6 months post (post ccm), | average minutes of AF/day | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Atrial Fibrillation (AF) Burden | Retrospective | pre ccm | 19.5 | Full Range 15.3 to 23.6 | average minutes of AF/day |
| Change in Atrial Fibrillation (AF) Burden | Retrospective | post ccm | 10.2 | Full Range 8.7 to 11.6 | average minutes of AF/day |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Retrospective | 2 | |
| Overall Study | COMPLETED | Retrospective | 2 | |
| Overall Study | NOT COMPLETED | Retrospective | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Retrospective | 0 | 0 |
| Total, other adverse events | Retrospective | 0 | 0 |
| Total, serious adverse events | Retrospective | 0 | 0 |
Source ClinicalTrials.gov
Papers7
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05704426
GET https://conductscience.org/api/trials/v1/NCT05704426/registered