Trial · NCT05708053
Cardio-protective Effect of Metformin in Patients Undergoing PCI
NCT05708053, Phase 3, Completed, Future University in Egypt
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cardio-protective Effect of Metformin in Patients Undergoing PCI. Trials, record NCT05708053. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05708053
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cardio-protective Effect of Metformin in Patients Undergoing PCI
- NCT number
- NCT05708053
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 80 participants, actual
- Lead sponsor
- Future University in Egypt
- Conditions
- Elective Percutaneous Coronary Intervention, Ischemic Reperfusion Injury
- Interventions
- Metformin
- First posted
- 2023-02-01
- Last updated
- 2026-10-09
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Postprocedural myocardial injury | 6 months | the occurrence of postprocedural myocardial injury, defined as a postprocedural elevation of CKMB or cTnI more than 1 times the 99 th percentile of the URL \[ 24 hours post PCI\] |
| Secondary | CK-MB | 24 hours post PCI | Mean peak values of CK-MB after intervention |
| Secondary | cTn | 24 hours post PCI | Mean peak values of cTnI after intervention |
| Secondary | LVEF in percent | Baseline- 6 months | Echo: to measure LVEF in percent |
| Secondary | LVMI in g/m2 | Baseline- 6 months | left ventricular mass index (LVMI) will be calculated in g/m2 using the sex and body surface area (m²) and measures of LVEDD in mm, IVSd in mm, PWd from the measures in the echocardiography |
| Secondary | GFR | Baseline- monthly- 6 months | glomerular filtration rate (GFR) will be calculated (unit ml/min) using age in years, sex, body weight in kilograms and serum creatinine in mg/dL |
| Secondary | Serum creatinine (SCr) | Baseline- monthly- 6 months | Serum creatinine (SCr) in mg/dL |
| Secondary | Lactate concentration | Baseline - 6 months | lactate concentration unit in mmol/L |
| Secondary | Glucometabolic State | Baseline - 6 months | Glucometabolic State using HbA1c (unit mmols/mol) |
| Secondary | Incidence of Cardiovascular Event | Baseline - 6 months | Cardiovascular events including major cardiac adverse events (MACE; death, recurrent MI, target lesion revascularization), stroke, non-elective hospitalizations for chest pain or heart failure, all recurrent coronary interventions, and internal cardiac defibrillator implantations. Mortality will be divided into cardiac and non- cardiac. Cardiac death will be divided into three categories: heart failure, sudden death, and others. |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05708053
GET https://conductscience.org/api/trials/v1/NCT05708053/registered