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Trial · NCT05710250

The Effects of Mindfulness Meditation on Brain Metabolism in the Limbic Regions Studied by Magnetic Resonance Spectroscopy

NCT05710250, Not applicable, Completed, University Hospital, Tours

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. The Effects of Mindfulness Meditation on Brain Metabolism in the Limbic Regions Studied by Magnetic Resonance Spectroscopy. Trials, record NCT05710250. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05710250

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
The Effects of Mindfulness Meditation on Brain Metabolism in the Limbic Regions Studied by Magnetic Resonance Spectroscopy
NCT number
NCT05710250
Status
Completed
Phases
Not applicable
Enrollment
30 participants, actual
Lead sponsor
University Hospital, Tours
Conditions
Behavior
Interventions
6-week MBSR program, 6-week muscular relaxation program
First posted
2023-02-02
Last updated
2026-02-13

Source ClinicalTrials.gov

Registered outcomes15

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange from Baseline in Glumatate concentrations (mM) at 8 Weeksbaseline and 8 weeksGlumatate concentrations (mM) are measured by magnetic resonance spectrocopy in left hippocampal formation
SecondaryChange in left hippocampal formation volumes (mm^3) measured on MRI 3D T1w sequencebaseline and 8 weeks
SecondaryChange in right amygdala volumes (mm^3) measured on MRI 3D T1w sequencebaseline and 8 weeks
SecondaryChange in posterior cingulate volumes (mm^3) measured on MRI 3D T1w sequencebaseline and 8 weeks
SecondaryChang in overall brain volume measured on MRI 3D T1w sequencebaseline and 8 weeks
SecondaryChange in score the Feeling of knowing task (FOK task)baseline and 8 weks
FOK task for episodic memory performance includes 4 distincts steps : (1) a learning phase of a 60 pairs of words, (2) a cued recall phase (number of correct recalls /60 ; number of incorrect recalls /60), (3) feeling of knowing phase, (4) recognition phase (number of correct recognition /60 ; number of incorrect recognition /60)
SecondaryChange in score of the Trail Making Test (TMT)baseline and 8 weeks
TMT consists of two parts. In the first part (A), the subject must connect with a pen in the correct order 25 numbers from 1 to 25, which are distributed randomly. In the second part (B), the subject must connect with a pencil in the correct order an alternation of 13 numbers from 1 to 13 and 12 letters from A to L, which are also distributed randomly. The time in seconds to complete each part is measured.
SecondaryChange in score of Stroop testbaseline and 8 weeksThe test includes 3 phases. In each one, participant have to give maximum of correct answer. Score ranges from 0 to 100 for each phase
SecondaryChange in score of N-Back testBaseline and at 8 weeksNumber of correct answer (yes or no). Total score /23
SecondaryChange in score of attentional network test (ANT)baseline and 8 weeks
Test (ANT) is a computerized testing measure that analyses the three components of attention network : alerting, orienting, executive control. Each of these three attention components is measured in time.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests7

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
1-Back TaskSecondary outcomeConductCognition
2-Back TaskSecondary outcomeConductCognition
Attention Network TestSecondary outcomeConductCognition
Judgments of Learning TaskSecondary outcomeConductCognition
Stroop Color-Word TestSecondary outcomeConductCognition
Trail Making Test ASecondary outcomeConductCognition
Trail Making Test BSecondary outcomeConductCognition

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05710250

GET https://conductscience.org/api/trials/v1/NCT05710250/registered