Trial · NCT05733403
Comparison of Hemodynamic Results of Two Different Fluid Managements
NCT05733403, Not applicable, Unknown, Istanbul University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Hemodynamic Results of Two Different Fluid Managements. Trials, record NCT05733403. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05733403
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Hemodynamic Results of Two Different Fluid Managements
- NCT number
- NCT05733403
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 40 participants, estimated
- Lead sponsor
- Istanbul University
- Conditions
- Perioperative Fluid Management
- Interventions
- isotonic solution, Noradrenaline
- First posted
- 2023-02-17
- Last updated
- 2023-10-23
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Cardiac index | during surgery | Cardiac index (CI) is a haemodynamic parameter that relates the cardiac output (CO) from left ventricle in one minute to body surface area (BSA),thus relating heart performance to the size of the individual. The unit of measurement is litres per minute per square metre (L/min/m2). |
| Secondary | Number of bolus administrations of noradrenaline | during surgery | For the MAP group, if MAP is still below 65 mmHg despite a bolus of 250ml isotonic fluid, a bolus of 4mcg noradrenaline will be administered, if no response, 4mcg noradrenaline will be repeated. For the SVV Group, a 4 mcg bolus of noradrenaline will be given if MAP\< 65 mmHg despite the SVV falling below 14% with isotonic boluses. |
| Secondary | Number of bolus administrations of isotonic fluid | during surgery | For the MAP group, the number of administrations of 250 ml of isotonic fluid delivered in 10 minutes when MAP \< 65 mmHg For the SVV group, the number of administrations of 250 ml of isotonic fluid administered in 10 minutes when SVV≥ 14% |
| Secondary | The Number of Hypotensive Episodes | during surgery | The number of times the MAP value falls below 65mmHg during surgery |
| Secondary | Intraoperative Fluid Balance | during surgery | the difference between the amount of urine output and the amount of bleeding from the amount of fluid given |
| Secondary | Plasma iNOS Levels | Up to 6 hours | difference in serum iNOS levels preoperatively and after removal of mammoplasty material |
| Secondary | Lactate value | Up to 6 hours | Values measured by perioperative arterial blood gas analysis |
| Secondary | Base deficit value | Up to 6 hours | Values measured by perioperative arterial blood gas analysis |
| Secondary | Creatinine value | Preoperative and Postoperative 1st day | Blood level is checked on the preoperative and postoperative 1st day |
| Secondary | Urea value | Preoperative and Postoperative 1st day | Blood level is checked on the preoperative and postoperative 1st day |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05733403
GET https://conductscience.org/api/trials/v1/NCT05733403/registered