Trial · NCT05744635
Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients
NCT05744635, Unknown, Chiesi Hungary Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients. Trials, record NCT05744635. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05744635
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients
- NCT number
- NCT05744635
- Status
- Unknown
- Enrollment
- 110 participants, estimated
- Lead sponsor
- Chiesi Hungary Ltd.
- Conditions
- Liver Failure
- Interventions
- Tacrolimus
- First posted
- 2023-02-27
- Last updated
- 2024-08-22
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pharmacokinetic profile TL | 12 months | To compare the trough level (TL) of different tacrolimus containing medications to Envarsus at each visit |
| Primary | Pharmacokinetic profile TDD | 12 months | To compare the total daily dose (TDD) of different tacrolimus containing medications to Envarsus at each visit |
| Primary | Pharmacokinetic profile C/D | 12 months | To compare the ration of TL and TDD (C/D) of different tacrolimus containing medications to Envarsus at each visit |
| Secondary | Liver function GGT | 12 months | Changes in Gamma glutamine transferase (GGT) levels compared to baseline. |
| Secondary | Liver function AP | 12 months | Changes in Alcalic phosphatase (AP) levels compared to baseline. |
| Secondary | Liver function GOT | 12 months | Changes in Glutamyl oxaloacetic transaminase (GOT) levels compared to baseline. |
| Secondary | Liver function GPT | 12 months | Changes in Glutamyl pyruvic transaminase (GPT) levels compared to baseline. |
| Secondary | Renal function | 12 months | Change in the estimated glomerular filtration rate (eGFR) compared to baseline. |
| Secondary | Kinetics and function | 12 months | To assess the possible relation of liver function parameters and eGFR to C/D (blood concentration and daily dosage) |
| Secondary | Rejection | 12 months | Incidence of acute graft rejection during the study |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05744635
GET https://conductscience.org/api/trials/v1/NCT05744635/registered