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Trial · NCT05748561

Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.

NCT05748561, Phase 2, Phase 3, Unknown, Asociación para Evitar la Ceguera en México

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial. Trials, record NCT05748561. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05748561

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.
NCT number
NCT05748561
Status
Unknown
Phases
Phase 2, Phase 3
Enrollment
18 participants, estimated
Lead sponsor
Asociación para Evitar la Ceguera en México
Conditions
Toxic Optic Neuropathy, Treatment, Methylprednisolone, Erythropoietin
Interventions
Recombinant human erythropoietin 4,000 UI and 2,000 UI, Methylprednisolone succinate 500 mg
First posted
2023-02-28
Last updated
2023-02-28

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange from Baseline Visual CapacityInitial visit, 2-week visit, 1-month visit, 3-month visitBest corrected visual acuity
SecondaryChange from Baseline Color visionInitial visit, 2-week visit, 1-month visit, 3-month visitColor vision as measured by Ishihara plates
SecondaryChange from Baseline Visual field defectInitial visit, 2-week visit, 1-month visit, 3-month visitVisual fields as measured by Goldmann perimetry
SecondaryChange from Baseline Oct pRNFL (microns)Initial visit, 3-month visitNerve fiber thickness as measured by OCT

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers15

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
3191081BACKGROUNDPubMed
6889696BACKGROUNDPubMed
16040592BACKGROUNDPubMed
18045860BACKGROUNDPubMed
19668477BACKGROUNDPubMed
20890611BACKGROUNDPubMed
22127151BACKGROUNDPubMed
24986593BACKGROUNDPubMed
25159832BACKGROUNDPubMed
25605544BACKGROUNDPubMed

1 to 10 of 15

See all 15 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05748561

GET https://conductscience.org/api/trials/v1/NCT05748561/registered