Trial · NCT05762003
Czech Pharmaco-epidemiological Study on Disease Modifying Drugs
NCT05762003, Completed, IMPULS Endowment Fund
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Czech Pharmaco-epidemiological Study on Disease Modifying Drugs. Trials, record NCT05762003. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05762003
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Czech Pharmaco-epidemiological Study on Disease Modifying Drugs
- NCT number
- NCT05762003
- Status
- Completed
- Enrollment
- 17,478 participants, actual
- Lead sponsor
- IMPULS Endowment Fund
- Conditions
- Multiple Sclerosis
- Interventions
- interferons, glatiramer acetate, teriflunomide, dimethyl fumarate, alemtuzumab, cladribine, fingolimod, ponesimod, rituximab, ocrelizumab, ofatumumab, natalizumab
- First posted
- 2023-03-09
- Last updated
- 2023-03-09
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Effectiveness in relapses | 1 year from DMD initiation | Measurement of annualized relapse rate (ARR) in patients on different DMDs. |
| Primary | Effectiveness EDSS | 1 year from DMD initiation | Description of disability measured by Expanded Disability Status Scale (EDSS) of values 0 to 10, where 0 represents no neurological disability due to multiple sclerosis (MS), and 10 represents death due to MS. The EDSS is commonly used among clinicians, and described by Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983; 33(11): 1444-1452. |
| Secondary | Description of baseline characteristics of patients treated by different DMDs at the time of DMT initiation | Baseline | Baseline characteristics (age, sex, disease duration, previous treatment, type of MS) of patients treated with different DMDs |
| Secondary | Description of termination of different DMDs treatment | Day of DMD termination, assessed up to 15 years | Number of patients that terminate treatment on particular DMDs |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05762003
GET https://conductscience.org/api/trials/v1/NCT05762003/registered