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Trial · NCT05790915

Registered outcomes30

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryImpact of standardized interventions in respiratory dysfunction on 48-hour delta SOFA with evaluation of the effectiveness of the interventions performed.48 hours
Lung protective ventilation: Tidal volume = 6 ml/kg; Plateau pressure \< 28 mmHg; driving pressue \< 16 cm H2O; Mechanical power \< 16 Joules/min; Prevention of self-inflicted lung injury (P-SILI): ROX index \> 4.8 and HACOR \< 5. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with respiratory dysfunction and effective intervention / Number of patients with respiratory dysfunction X 100
PrimaryImpact of standardized interventions in hemodinamic dysfunction on 48-hour delta SOFA48 hour
SOSD (salvage, optimization, stabilization and de-escalation ) protocol; mean arterial pressoric taget of at least 65 mm Hg, Lactate serum level \< 19 mg/dL. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hemodinamic dysfunction and effective intervention / Number of patients with hemodinamica dysfunction X 100
PrimaryImpact of standardized interventions in neurologic dysfunction on 48-hour delta SOFA48 hour
Image: cranial CT; Electroencephalografic monitoring and RASS Score between -1 and +1 The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with neurologic dysfunction and effective intervention / Number of patients with neurologic dysfunction X 100
PrimaryImpact of standardized interventions in hematologic dysfunction on 48-hour delta SOFA48 hour
Basic disease approach; avoid drugs that interfere with coagulation; Platelet transfusion in case of hemohhage; DDAVP when indicated. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hematologic dysfunction and effective intervention / Number of patients with hematologic dysfunction X 100
PrimaryImpact of standardized interventions iin renal dysfunction on 48-hour delta SOFA48 hour
Avoid nephotoxic drugs; Mantain mean arterial blood pressure \> 65 mmHg The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with renal dysfunction and effective intervention / Number of patients with renal dysfunction X 100
PrimaryImpact of standardized interventions in hepatic dysfunction on 48-hour delta SOFA48 hour
Avoid hepatotoxic drugs;basic disease approach The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hepatic dysfunction and effective intervention / Number of patients with hepatic dysfunction X 100
SecondaryImpact of standardized interventions in respiratory dysfunction on ICU length of stay28 days
Lung protective ventilation: Tidal volume 6 ml/kg; Pateau pressure \< 28 mmHg; driving pressue \< 16 cm H2O; Mechanical power \< 16 Joules/min; Prevention of self-inflicted lung injury (P-SILI): ROX index \> 4.8 and HACOR \< 5. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with respiratory dysfunction and effective intervention / Number of patients with respiratory dysfunction X 100
SecondaryImpact of standardized interventions in hemodinamic dysfuction on ICU length of stay28 days
SOSD (salvage, optimization, stabilixation and de-escalation ) protocol; mean arterial pressoric taget of at least 65 mm Hg, Lactate serum level \< 19 mg/dL. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hemodinamic dysfunction and effective intervention / Number of patients with hemodinamic dysfunction X 100
SecondaryImpact of standardized interventions in neurologic dysfunction on ICU length of stay28 days
Image: cranial CT; Electroencephalografic monitoring and RASS Score between -1 and +1 The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with neurologic dysfunction and effective intervention / Number of patients with neurologic dysfunction X 100
SecondaryImpact of standardized interventions in hematologic dysfunction on ICU length of stay28 days
Basic disease approach; avoid drugs that interfere with coagulation; Platelet transfusion in case of hemohhage; DDAVP when indicated. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hematologic dysfunction and effective intervention / Number of patients with hematologic dysfunction X 100
SecondaryImpact of standardized interventions iin renal dysfunction on ICU length of stay28 days
Avoid nephotoxic drugs; Mantain mean arterial blood pressure \> 65 mmHg The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with renal dysfunction and effective intervention / Number of patients with renal dysfunction X 100
SecondaryImpact of standardized interventions in hepatic dysfunction on ICU length of stay28 days
Avoid hepatotoxic drugs;basic disease approach The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hepatic dysfunction and effective intervention / Number of patients with hepatic dysfunction X 100
SecondaryImpact of standardized interventions in respiratory dysfunction on vasopressor-free days28 days
Lung protective ventilation: Tidal volume 6 ml/kg; Pateau pressure \< 28 mmHg; driving pressue \< 16 cm H2O; Mechanical power \< 16 Joules/min; Prevention of self-inflicted lung injury (P-SILI): ROX index \> 4.8 and HACOR \< 5. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with respiratory dysfunction and effective intervention / Number of patients with respiratory dysfunction X 100
SecondaryImpact of standardized interventions in hemodinamic dysfuction on vasopressor-free days28 days
SOSD (salvage, optimization, stabilixation and de-escalation ) protocol; mean arterial pressoric taget of at least 65 mm Hg, Lactate serum level \< 19 mg/dL. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hemodinamic dysfunction and effective intervention / Number of patients with hemodinamic dysfunction X 100
SecondaryImpact of standardized interventions in neurologic dysfunction on vasopressor-free days28 days
Image: cranial CT; Electroencephalografic monitoring and RASS Score between -1 and +1 The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with neurologic dysfunction and effective intervention / Number of patients with neurologic dysfunction X 100
SecondaryImpact of standardized interventions in hematologic dysfunction on vasopressor-free days28 days
Basic disease approach; avoid drugs that interfere with coagulation; Platelet transfusion in case of hemohhage; DDAVP when indicated. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hematologic dysfunction and effective intervention / Number of patients with hematologic dysfunction X 100
SecondaryImpact of standardized interventions iin renal dysfunction on vasopressor-free days28 days
Avoid nephotoxic drugs; Mantain mean arterial blood pressure \> 65 mmHg The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with renal dysfunction and effective intervention / Number of patients with renal dysfunction X 100
SecondaryImpact of standardized interventions in hepatic dysfunction on vasopressor-free days28 days
Avoid hepatotoxic drugs;basic disease approach The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hepatic dysfunction and effective intervention / Number of patients with hepatic dysfunction X 100
SecondaryImpact of standardized interventions in respiratory dysfunction on ventilator-free days28 days
Lung protective ventilation: Tidal volume 6 ml/kg; Pateau pressure \< 28 mmHg; driving pressue \< 16 cm H2O; Mechanical power \< 16 Joules/min; Prevention of self-inflicted lung injury (P-SILI): ROX index \> 4.8 and HACOR \< 5. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with respiratory dysfunction and effective intervention / Number of patients with respiratory dysfunction X 100
SecondaryImpact of standardized interventions in hemodinamic dysfuction on ventilator-free days28 days
SOSD (salvage, optimization, stabilixation and de-escalation ) protocol; mean arterial pressoric taget of at least 65 mm Hg, Lactate serum level \< 19 mg/dL. The effectiveness of the interventions on organic disfunction will be evaluated through the formula: Number of patients with hemodinamic dysfunction and effective intervention / Number of patients with hemodinamic dysfunction X 100

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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