Trial · NCT05820880
Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension
NCT05820880, Phase 3, Completed, Institut de Recherches Internationales Servier
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension. Trials, record NCT05820880. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05820880
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension
- NCT number
- NCT05820880
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 532 participants, actual
- Lead sponsor
- Institut de Recherches Internationales Servier
- Conditions
- Hypertension
- Interventions
- Fixed [Per/Ind/Aml], Free [Per/Ind + Aml]
- First posted
- 2023-04-20
- Last updated
- 2024-07-25
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Sitting SBP change after two months of treatment | Baseline safety visit, Month 2 follow-up visit | Office sitting Systolic Blood Pressure (SBP) change from baseline to last post-baseline value over the period from Month 0 to month 2 |
| Secondary | Sitting SBP change from month 2 to month 4 | Month 2 follow-up visit, Month 4 follow-up visit | Office sitting Systolic Blood Pressure (SBP) change from month 2 to month 4 |
| Secondary | Sitting SBP change from month 4 to month 6 | Month 4 follow-up visit, Month 6 follow-up visit | Office sitting Systolic Blood Pressure (SBP) change from month 4 to month 6 |
| Secondary | Sitting DBP change after two months of treatment | Baseline safety visit, Month 2 follow-up visit | Office sitting Diastolic Blood Pressure (DBP) change from baseline to last post-baseline value over the period from Month 0 to month 2 |
| Secondary | Sitting DBP change from month 2 to month 4 | Month 2 follow-up visit, Month 4 follow-up visit | Office sitting Diastolic Blood Pressure (DBP) change from month 2 to month 4 |
| Secondary | Sitting DBP change from month 4 to month 6 | Month 4 follow-up visit, Month 6 follow-up visit | Office sitting Diastolic Blood Pressure (DBP) change from month 4 to month 6 |
| Secondary | Sitting Mean Arterial Pressure change after two months of treatment | Baseline safety visit, Month 2 follow-up visit | Sitting Mean Arterial Pressure (MAP) change from baseline to last post-baseline value over the period from Month 0 to month 2 with MAP=2/3 DBP+1/3 SBP |
| Secondary | Sitting Mean Arterial Pressure change from month 2 to month 4 | Month 2 follow-up visit, Month 4 follow-up visit | Sitting Mean Arterial Pressure (MAP) change from from month 2 to month 4 , with MAP=2/3 DBP+1/3 SBP |
| Secondary | Sitting Mean Arterial Pressure change from month 4 to month 6 | Month 4 follow-up visit, Month 6 follow-up visit | Sitting Mean Arterial Pressure (MAP) change from from month 4 to month 6, with MAP=2/3 DBP+1/3 SBP |
| Secondary | Sitting Pulse Pressure change after two months of treatment | Baseline safety visit, Month 2 follow-up visit | Sitting Pulse Pressure change from baseline to last post-baseline value over the period from Month 0 to month 2, with Pulse Pressure=SBP-DBP |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 38660708 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05820880
GET https://conductscience.org/api/trials/v1/NCT05820880/registered