Effects of Weight Loss Management on Cognitive Function in Elderly Women With Obesity
NCT05841173, Not applicable, Unknown, Federal State Budgetary Scientific Institution
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effects of Weight Loss Management on Cognitive Function in Elderly Women With Obesity | ClinicalTrials.gov |
| NCT number | NCT05841173 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 200 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Federal State Budgetary Scientific Institution | ClinicalTrials.gov |
| Conditions | Obesity, Cognitive Change | ClinicalTrials.gov |
| Interventions | "PanTrek", Physical Trainings, Placebo, Diet | ClinicalTrials.gov |
| First posted | 2023-05-03 | ClinicalTrials.gov |
| Last updated | 2023-05-06 | ClinicalTrials.gov |
Registered outcomes 21
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change from baseline body weight at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The dynamics of body weight | ClinicalTrials.gov |
| Primary | Change from baseline Montreal Cognitive Assessment (MoCa) test scores at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the cognitive testing results | ClinicalTrials.gov |
| Primary | Change from baseline Trail Making Test (TMT) a&b test scores at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the cognitive testing results (normal range - less than 78 and 273 seconds (=scores)). | ClinicalTrials.gov |
| Primary | Change from baseline Word recall test scores at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the cognitive testing results (normal range as 45 words (=scores) and more out of 5 repetitions). Minimal - 0 (worse result), maximal score - 50 (excellent result). | ClinicalTrials.gov |
| Primary | Change from baseline Mean response time in the test "Schulte tables" at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the cognitive testing results | ClinicalTrials.gov |
| Primary | Change from baseline The Stroop Color and Word Test results at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the cognitive testing results | ClinicalTrials.gov |
| Primary | Change from baseline Verbal fluency test results at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the cognitive testing results | ClinicalTrials.gov |
| Secondary | Change from baseline fat mass at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the fat mass according to the bioimpedance analysis | ClinicalTrials.gov |
| Secondary | Change from baseline skeletal muscle mass at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in the skeletal muscle mass according to the bioimpedance analysis | ClinicalTrials.gov |
| Secondary | Change from baseline visceral fat at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes in visceral fat according to the bioimpedance analysis | ClinicalTrials.gov |
| Secondary | Change from baseline total cholesterol serum levels at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of total cholesterol serum levels | ClinicalTrials.gov |
| Secondary | Change from baseline LDL-cholesterol serum levels at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of LDL-cholesterol serum levels | ClinicalTrials.gov |
| Secondary | Change from baseline HOMA-IR (homeostasis model assessment - insulin resistance) index at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of HOMA-IR index | ClinicalTrials.gov |
| Secondary | Change from baseline C-reactive protein (CRP) serum levels at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of CRP serum levels | ClinicalTrials.gov |
| Secondary | Change from baseline Tumor Necrosis Factor Alpha (TNFa) serum levels at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of TNFa serum levels | ClinicalTrials.gov |
| Secondary | Change from baseline systolic blood pressure (SBP) at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of SBP | ClinicalTrials.gov |
| Secondary | Change from baseline diastolic blood pressure (DBP) at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of DBP | ClinicalTrials.gov |
| Secondary | Change from baseline grip strength at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of grip strength measured by grip dynamometer on the leading hand | ClinicalTrials.gov |
| Secondary | Change from baseline Six Minute Walk Test distance at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of Six Minute Walk Test results | ClinicalTrials.gov |
| Secondary | Change from baseline Hamilton Anxiety Rating Scale at 12 weeks | Baseline (visit 1) and after 12 weeks (visit 2) | The changes of Hamilton Anxiety Rating Scale results (normal range - 6 scores and less). | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 17
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 30569063 | BACKGROUND | PubMed |
| 30863030 | BACKGROUND | PubMed |
| 31051329 | BACKGROUND | PubMed |
| 31181771 | BACKGROUND | PubMed |
| 31216732 | BACKGROUND | PubMed |
| 31257976 | BACKGROUND | PubMed |
| 31286668 | BACKGROUND | PubMed |
| 31503023 | BACKGROUND | PubMed |
| 31865598 | BACKGROUND | PubMed |
| 32019161 | BACKGROUND | PubMed |
| 32368021 | BACKGROUND | PubMed |
| 33336232 | BACKGROUND | PubMed |
| 34264558 | BACKGROUND | PubMed |
| 34562568 | BACKGROUND | PubMed |
| 34742925 | BACKGROUND | PubMed |
| 35276979 | BACKGROUND | PubMed |
| 36286917 | BACKGROUND | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 5
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Ordered Number Search Task | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
| Verbal Fluency | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)