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Trial · NCT05856526

Results by group68

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Week 16 (Yes/No)Placebo0.13395% Confidence Interval 0.037 to 0.379proportion of participants
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Week 16 (Yes/No)Spesolimab0.28695% Confidence Interval 0.153 to 0.471proportion of participants
Key Secondary Endpoint: IGA Response, Defined as a Decrease of at Least 1-grade Absolute Change in IGA Score From Baseline at Week 16 (Yes/No)Placebo0.40095% Confidence Interval 0.198 to 0.643proportion of participants
Key Secondary Endpoint: IGA Response, Defined as a Decrease of at Least 1-grade Absolute Change in IGA Score From Baseline at Week 16 (Yes/No)Spesolimab0.35795% Confidence Interval 0.207 to 0.542proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)PlaceboWeek 40.00095% Confidence Interval 0.000 to 0.204proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)SpesolimabWeek 40.03695% Confidence Interval 0.006 to 0.177proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)PlaceboWeek 80.00095% Confidence Interval 0.000 to 0.204proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)SpesolimabWeek 80.00095% Confidence Interval 0.000 to 0.121proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)PlaceboWeek 120.00095% Confidence Interval 0.000 to 0.204proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)SpesolimabWeek 120.03695% Confidence Interval 0.006 to 0.177proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)PlaceboWeek 160.00095% Confidence Interval 0.000 to 0.204proportion of participants
IGA Score of 0 or 1 at Weeks 4, 8, 12 and 16 (Yes/No)SpesolimabWeek 160.03695% Confidence Interval 0.006 to 0.177proportion of participants
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Weeks 4, 8, and 12 (Yes/No)PlaceboIASI response at Week 40.06795% Confidence Interval 0.012 to 0.298proportion of participants
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Weeks 4, 8, and 12 (Yes/No)SpesolimabIASI response at Week 40.25095% Confidence Interval 0.127 to 0.434proportion of participants
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Weeks 4, 8, and 12 (Yes/No)PlaceboIASI response at Week 80.06795% Confidence Interval 0.012 to 0.298proportion of participants
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Weeks 4, 8, and 12 (Yes/No)SpesolimabIASI response at Week 80.28695% Confidence Interval 0.153 to 0.471proportion of participants
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Weeks 4, 8, and 12 (Yes/No)PlaceboIASI response at Week 120.13395% Confidence Interval 0.037 to 0.379proportion of participants
IASI Response, Defined as a Decrease of at Least 50% Absolute Change in IASI Score From Baseline at Weeks 4, 8, and 12 (Yes/No)SpesolimabIASI response at Week 120.28695% Confidence Interval 0.153 to 0.471proportion of participants
IASI-E Subscore Response, Defined as a Decrease of at Least 50% Absolute Change in IASI-E Subscore at Weeks 4, 8, 12, and 16 (Yes/No)PlaceboIASI-E subscore response at Week 40.00095% Confidence Interval 0.000 to 0.204proportion of participants
IASI-E Subscore Response, Defined as a Decrease of at Least 50% Absolute Change in IASI-E Subscore at Weeks 4, 8, 12, and 16 (Yes/No)SpesolimabIASI-E subscore response at Week 40.25095% Confidence Interval 0.127 to 0.434proportion of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT05856526/results