Trial · NCT05865470
Age-dependent Effects of Smoked and Oral Delta-9-THC
NCT05865470, Phase 1, Recruiting, University of California, Los Angeles
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Age-dependent Effects of Smoked and Oral Delta-9-THC. Trials, record NCT05865470. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05865470
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Age-dependent Effects of Smoked and Oral Delta-9-THC
- NCT number
- NCT05865470
- Status
- Recruiting
- Phases
- Phase 1
- Enrollment
- 103 participants, estimated
- Lead sponsor
- University of California, Los Angeles
- Conditions
- Pain, Abuse, Drug, Intoxication; Cannabinoids
- Interventions
- Cannabis, Dronabinol, Smoked Placebo, Oral Placebo
- First posted
- 2023-05-18
- Last updated
- 2026-01-07
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Subject-rated drug effects | 6 hours | Average and peak subjective ratings of drug effects associated with abuse liability and intoxication as measured using visual analogue scales (VAS; 1-100mm). |
| Primary | Analgesia as measured using the Cold Pressor Test | 6 hours | Peak and average pain threshold and tolerance assessed using the Cold Pressor Test |
| Primary | Impairment | 6 hours | The primary outcome measure for performance will be the peak difference from baseline scores of the Global Impairment Score |
| Primary | Pharmacokinetics of THC and metabolites | 6 hours | Plasma levels of THC, 11-OH-THC, and THCCOOH |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01DA057252 | Age-and sex-dependent pharmacodynamics and pharmacokinetics of oral and smoked delta-9-THC | COOPER, ZIVA D | UNIVERSITY OF CALIFORNIA LOS ANGELES | NATIONAL INSTITUTE ON DRUG ABUSE | 2022 to 2025 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05865470
GET https://conductscience.org/api/trials/v1/NCT05865470/registered