Trial · NCT05901467
Recall by Genotype: Neuropeptide Stimulation
NCT05901467, Phase 1, Terminated, Stephanie B. Seminara, MD; results first posted 2025-11-18
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Recall by Genotype: Neuropeptide Stimulation. Trials, record NCT05901467. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05901467
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Recall by Genotype: Neuropeptide Stimulation
- NCT number
- NCT05901467
- Status
- Terminated
- Phases
- Phase 1
- Enrollment
- 16 participants, actual
- Lead sponsor
- Stephanie B. Seminara, MD
- Conditions
- Reproductive Disorder
- Interventions
- kisspeptin 112-121, GnRH
- First posted
- 2023-06-13
- Last updated
- 2026-03-06
- Results first posted
- 2025-11-18
- Limitations and caveats
- No participants underwent the intervention. This trial was terminated because the study team no longer had access to the study drugs.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Endogenous LH Pulse Amplitude | Hours 0-8 | Average amplitude of LH pulses at baseline |
| Primary | Kisspeptin-induced LH Pulse Amplitude | Hours 8-11 | Amplitude of LH pulse in response to kisspeptin |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Endogenous LH Pulse Amplitude | Hours 0-8 | No participants underwent the intervention. This trial was terminated because the study team no longer had access to the study drugs. | mIU/mL | MEAN |
| PRIMARY | Kisspeptin-induced LH Pulse Amplitude | Hours 8-11 | No participants underwent the intervention. This trial was terminated because the study team no longer had access to the study drugs. | mIU/mL | MEAN |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Kisspeptin, GnRH | 16 | |
| Overall Study | COMPLETED | Kisspeptin, GnRH | 0 | |
| Overall Study | NOT COMPLETED | Kisspeptin, GnRH | 16 |
Source ClinicalTrials.gov
Adverse events1
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Upper respiratory infection | Infections and infestations | Kisspeptin, GnRH | 1 | 16 |
Source ClinicalTrials.gov
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Kisspeptin, GnRH | 0 | 16 |
| Total, other adverse events | Kisspeptin, GnRH | 1 | 16 |
| Total, serious adverse events | Kisspeptin, GnRH | 0 | 16 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| P50HD104224 | The Massachusetts General Hospital Harvard Center for Reproductive Medicine | SEMINARA, STEPHANIE BETH | MASSACHUSETTS GENERAL HOSPITAL | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2021 to 2025 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05901467
GET https://conductscience.org/api/trials/v1/NCT05901467/registered