Trial · NCT05903859
Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
NCT05903859, Phase 3, Recruiting, University of Miami
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI). Trials, record NCT05903859. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05903859
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
- NCT number
- NCT05903859
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 90 participants, estimated
- Lead sponsor
- University of Miami
- Conditions
- Infertility, Male
- Interventions
- Probenecid 500 Milligrams (mg), probenecid 250 Milligrams (mg), Placebo
- First posted
- 2023-06-15
- Last updated
- 2026-03-02
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in total motile sperm count | Baseline, up to 6 months post intervention, up to 6 months post follow up. | The total sperm count will be assessed by calculating semen volume times sperm count times sperm motility percentage.The unit of measurement is in Millions. |
| Secondary | Change in percentage sperm DNA fragmentation | Baseline, up to 6 months post intervention, up to 6 months post follow up. | The percentage of DNA fragmented sperm in specimen |
| Secondary | Change in percentage of sperm viability | Baseline, up to 6 months post intervention, up to 6 months post follow up. | The percentage of viable sperm ion specimen |
| Secondary | Change in semen inflammasome markers | Baseline, up to 6 months post intervention, up to 6 months post follow up. | Markers will be measured in picogram/milliliter units |
| Secondary | Number of treatment-related adverse events | Up to 6 months post follow up. | Treatment-related adverse events will be assessed by the treating physician using Common Terminology Criteria for Adverse Events 4 (CTCAE 4) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 28464732 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05903859
GET https://conductscience.org/api/trials/v1/NCT05903859/registered