Trial · NCT05911477
Recombinant Human Bone Morphogenetic Protein-2(rhBMP-2) in Patients With Osteoporosis After Lumbar Fusion
NCT05911477, Not applicable, Unknown, Xijing Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Recombinant Human Bone Morphogenetic Protein-2(rhBMP-2) in Patients With Osteoporosis After Lumbar Fusion. Trials, record NCT05911477. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05911477
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Recombinant Human Bone Morphogenetic Protein-2(rhBMP-2) in Patients With Osteoporosis After Lumbar Fusion
- NCT number
- NCT05911477
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 76 participants, estimated
- Lead sponsor
- Xijing Hospital
- Conditions
- Osteoporosis, Spinal Fusion
- Interventions
- RhBMP-2
- First posted
- 2023-06-22
- Last updated
- 2023-06-22
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Fusion rate at 6 months | 6 months follow-up | 1. \<5°of angular motion, ≤3 mm of translation from lumbar spine dynamic radiographs 2. Bridging bone connecting the adjacent vertebral bodies either through the implants or around the implants, and an absence of radiolucent lines around \>50% of either implant from computed tomography (CT) scans of lumbar |
| Primary | Fusion rate at 3 months | 3 months follow-up | \<5°of angular motion, ≤3 mm of translation from lumbar spine dynamic radiographs of radiolucent lines around \>50% of either implant |
| Secondary | Visual Analog Score for low back pain (VAS-B) | pre- and post-operative immediately, 3- and 6- months follow-up | range from 0-10, a higher score means a worse outcome.Short Form Survey (SF-36) |
| Secondary | Visual Analog Score for leg pain (VAS-L) | pre- and post-operative immediately, 3- and 6- months follow-up | range from 0-10, a higher score means a worse outcome. |
| Secondary | Oswestry disability index (ODI) | pre-operatively, 3- and 6-months follow-up | range from 0-100%, a higher score means a worse outcome. |
| Secondary | 36-Item Short Form Survey (SF-36) | pre-operatively, 3- and 6-months follow-up | As part of the Medical Outcomes Study (MOS), a multi-year, multi-site study to explain variations in patient outcomes, RAND developed the 36-Item Short Form Health Survey (SF-36) in 1992. SF-36 is a set of generic, coherent, and easily administered quality-of-life measures. |
| Secondary | Incidence of complications | post-operative immediately, 3- and 6- months follow-up | infection, revision surgery, etc. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05911477
GET https://conductscience.org/api/trials/v1/NCT05911477/registered