Trial · NCT05922995
The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)
NCT05922995, Early phase 1, Terminated, Brigham and Women's Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD). Trials, record NCT05922995. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05922995
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)
- NCT number
- NCT05922995
- Status
- Terminated
- Phases
- Early phase 1
- Enrollment
- 20 participants, actual
- Lead sponsor
- Brigham and Women's Hospital
- Conditions
- REM Behavior Disorder
- Interventions
- Tasimelteon
- First posted
- 2023-06-28
- Last updated
- 2025-10-09
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Daily Sleep Diary - Visual Fill-In | Daily for 8 weeks (both baseline and treatment phases) | The daily sleep diary contains a diagram similar to a calendar that the participant can track their intake of caffeine, medicine, and alcohol, if they exercised, when they went to bed, fell asleep, or took a nap, and when they woke up. All recordings will be measured as number of events/time of day. |
| Primary | Daily Sleep Diary - Time Keeping | Daily for 8 weeks (both baseline and treatment phases) | The daily sleep diary also contains a series of questions. Some of them ask the participant to record the time the diary is completed, the time they took the study drug, and the time that they think they had a dream reenactment event. All of these will be recorded in 24:00 format. |
| Primary | Daily Sleep Diary - Sleep Questions | Daily for 8 weeks (both baseline and treatment phases) | The daily sleep diary also asks participants subjective questions like did you sleep last night, did you wake up naturally, and did you take the study drug last night? These will be recorded as yes/no responses. |
| Primary | Daily Sleep Diary - Dream Enactment | Daily for 8 weeks (both baseline and treatment phases) | The daily sleep diary also asks participants to recall how many dream enactments they had the previous night if any at all. This will be recorded as a numerical value. |
| Secondary | Clinical Global Impression of Change | 1 Month after study | Investigator-rated Assessment of Global Improvement in participant symptoms |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers28
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05922995
GET https://conductscience.org/api/trials/v1/NCT05922995/papers?page=2