Trial · NCT05931276
CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
NCT05931276, Phase 3, Recruiting, VA Office of Research and Development
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes. Trials, record NCT05931276. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05931276
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
- NCT number
- NCT05931276
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 2,540 participants, estimated
- Lead sponsor
- VA Office of Research and Development
- Conditions
- End-Stage Kidney Disease, End-Stage Renal Disease
- Interventions
- Metoprolol Succinate, Carvedilol
- First posted
- 2023-07-05
- Last updated
- 2026-10-13
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time to major cardiovascular event | Randomization to time to event; average follow-up 3 years | The Primary outcome measure will be time to a non-fatal adverse cardiovascular event, defined as a composite outcome comprised of the first occurrence after randomization of any of the following: myocardial infarction, stroke, or hospitalization for heart failure, and all-cause mortality |
| Secondary | Non-fatal myocardial infarction | Randomization to time to event; average follow-up 3 years | Non-fatal myocardial infarction |
| Secondary | Non-fatal stroke | Randomization to time to event; average follow-up 3 years | Non-fatal stroke |
| Secondary | Hospitalization for heart failure | Randomization to time to event; average follow-up 3 years | Hospitalization for heart failure |
| Secondary | All-cause mortality | Randomization to time to event; average follow-up 3 years | All-cause mortality |
| Other | All-cause hospitalization | Randomization to time to event; average follow-up 3 years | All-cause hospitalization |
| Other | ED visit or hospitalization possibly related to low BP including falls, fractures, hypotension, or serious injury | Number of events; average follow-up 3 years | Number of emergency department visits or hospitalization for events that may be a consequence of low blood pressure or beta blocker excess or withdrawal including falls, fractures, hypotension, or serious injury |
| Other | Use of BP raising medications | Use of drug; average follow-up 3 years | Use and dose of midodrine |
| Other | ED or hospital visits for atrial fibrillation and uncontrolled rate | Randomization to time to event; average follow-up 3 yars | Emergency department visit or hospitalization for atrial fibrillation with uncontrolled rate (to capture poor control with beta blocker withdrawal) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 38419159 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05931276
GET https://conductscience.org/api/trials/v1/NCT05931276/registered