Trial · NCT05931601
Early Initiated Vasopressor Therapy in the Emergency Department
NCT05931601, Phase 3, Recruiting, Odense University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Early Initiated Vasopressor Therapy in the Emergency Department. Trials, record NCT05931601. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05931601
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Early Initiated Vasopressor Therapy in the Emergency Department
- NCT number
- NCT05931601
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 320 participants, estimated
- Lead sponsor
- Odense University Hospital
- Conditions
- Shock, Shock, Septic, Hypotension, Hypotension and Shock, Hypotension Symptomatic, Hypovolemia, Hypovolemic Shock, Hypovolemic
- Interventions
- Noradrenaline
- First posted
- 2023-07-05
- Last updated
- 2025-07-01
Source ClinicalTrials.gov
Registered outcomes20
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The primary outcome is the proportion of patients achieving either SBP >100 mmHg or MAP > 65 mmHg or a target blood pressure set by the treating physician at 90 (±15) minutes after inclusion. | At 90 minutes | Bed-side assessment during treatment and registered in the case report form. |
| Secondary | Number of intensive care unit (ICU) free days alive within 30 days | At 30 days | Data is extracted from the Danish national registries or the patient's electronic medical record. Note: Death will count as 0 days. |
| Secondary | Time without shock within 24 hours | At 24 hours | Bed-side assessment during treatment and registered in the case report form or by extraction from the patient's electronic medical record. |
| Secondary | 30-day all-cause mortality | At 30 days | Data is extracted from the Danish national registries or the patient's electronic medical records. |
| Secondary | In-hospital all-cause mortality | At hospital discharge, an average of 30 days efter inclusion | Data is extracted from the Danish national registries or the patient's electronic medical records. |
| Other | Proportion of patients receiving vasopressor at any point within 24 hours | At 24 hours | Bed-side assessment during treatment and registered in the case report form or by extraction from the patient's electronic medical record. |
| Other | Time to vasopressor initiation | At 30 days | Bed-side assessment during treatment and registered in the case report form or by extraction from the patient's electronic medical record. |
| Other | Hours of vasopressor infusion | At 30 days | Bed-side assessment during treatment and registered in the case report form or by extraction from the patient's electronic medical record. |
| Other | Proportion of patients with pulmonary oedema within 72 hours | At 72 hours | Bed-side assessment during treatment and registered in the case report form or by extraction from the patient's electronic medical record. |
| Other | Proportion of patients with acute kidney failure within 72 hours | At 72 hours | Bed-side assessment during treatment and registered in the case report form or by extraction from the patient's electronic medical record. |
1 to 10 of 20Source ClinicalTrials.gov
See all 20 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 40197397 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05931601
GET https://conductscience.org/api/trials/v1/NCT05931601/registered