Trial · NCT05957991
Danish Precocious Puberty Study - DAPP Study A National Cohort Study on Incidence and Etiologies for Precocious Puberty
NCT05957991, Not yet recruiting, Copenhagen University Hospital at Herlev
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Danish Precocious Puberty Study - DAPP Study A National Cohort Study on Incidence and Etiologies for Precocious Puberty. Trials, record NCT05957991. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05957991
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Danish Precocious Puberty Study - DAPP Study A National Cohort Study on Incidence and Etiologies for Precocious Puberty
- NCT number
- NCT05957991
- Status
- Not yet recruiting
- Enrollment
- 1,500 participants, estimated
- Lead sponsor
- Copenhagen University Hospital at Herlev
- Conditions
- Puberty, Precocious
- Interventions
- Metformin Hydrochloride tablet, Placebo, Lifestyle intervention, No lifestyle intervention
- First posted
- 2023-07-24
- Last updated
- 2023-07-24
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Incidence of CPP among all children referred to 18 Danish pediatric departments during a 3-year period | 3 years | Number of patients referred who have precocious puberty |
| Primary | BMI (SDS) at pubertal onset | 3 years | Adiposity in children with precocious puberty |
| Primary | Genome-wide methylation patterns in peripheral blood associated with CPP and treatment | 3 years | epigenetic alterations |
| Primary | Urinary EDC excretion profiles in CPP children compared to age-matched controls | 3 years | endocrine disrupting chemicals associated to early puberty |
| Primary | Randomised placebo controlled trial | 3 years | The effect of metformin and/or lifestyle intervention on pubertal development |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05957991
GET https://conductscience.org/api/trials/v1/NCT05957991/registered