Registered outcomes11

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

1 to 11 of 11

List	Outcome	Time frame	Description
Primary	Incidence and severity of adverse events (AE), rate of surgical delays, abnormal laboratory findings of clinical significance	Up to approximately 2 years
Primary	Pathological complete response (pCR) rates	Up to approximately 2 years	pCR is defined the 0% residual viable tumor cells in the primary tumor and sampled lymph nodes
Secondary	Major pathological response(MPR) rates	Up to approximately 2 years	MPR is defined the ≤10% residual viable tumor cells in the primary tumor and sampled lymph nodes
Secondary	Tumor regression grade(TRG)	Up to approximately 2 years
Secondary	R0 resection rate	Up to approximately 2 years
Secondary	Tumor descending stage rate	Up to approximately 2 years	Proportion of subjects whose tumor TNM stage decreased from baseline before surgery
Secondary	ORR	Up to approximately 2 years
Secondary	EFS	Up to approximately 2 years
Secondary	OS	Up to approximately 2 years
Secondary	PK	Up to approximately 2 years	Serum drug concentrations of cadonilimab and/or AK117 in individual subjects at different time points
Secondary	ADA	Up to approximately 2 years	Number of subjects with detectable anti-drug antibodies (ADA).

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNone stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT05960955/registered