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Trial · NCT05962255

Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure

NCT05962255, Phase 3, Completed, Wroclaw Medical University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure. Trials, record NCT05962255. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05962255

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure
NCT number
NCT05962255
Status
Completed
Phases
Phase 3
Enrollment
50 participants, actual
Lead sponsor
Wroclaw Medical University
Conditions
Acute Heart Failure, Congestion, Heart Failure
Interventions
Furosemide intravenous infusion, Continous intravenous infusion of 0.9% Sodium Chloride solution, Continous intravenous infusion of 5% Glucose solution
First posted
2023-07-27
Last updated
2024-06-21

Source ClinicalTrials.gov

Registered outcomes12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryUrine volume change at individual timepoints during first day of the procedure.24 hoursComparison of urine volume between the groups at individual timepoints during the first day of the procedure.
PrimaryUrine volume change at individual timepoints during second day of the procedure.48 hoursComparison of urine volume between the groups at individual timepoints during the second day of the procedure.
PrimaryUrine composition at individual time points.72 hoursComparison of urine composition (urinary sodium and urinary chloride) between the groups and its change during 72h
PrimaryCumulative urine output at 24 hours.24 hoursComparison of cumulative urine output between the groups at 24 hours.
PrimaryCumulative urine output at hours.48 hoursComparison of cumulative urine output between the groups at 48 hours.
PrimaryTotal dose of furosemide.48 hoursComparison of the total dose of furosemide between the groups at hours.
SecondaryTotal time on intravenous furosemide.3 monthsThe total time on intravenous furosemide between hospital admission and discharge will be calculated.
SecondaryRenin-Angiotensin-Aldosterone system activity.24 hoursComparison of the renin and aldosterone serum levels between the groups at the 24 hours.
SecondaryRenin-Angiotensin-Aldosterone system activity.48 hoursComparison of the renin and aldosterone serum levels between the groups at the 48 hours.
SecondaryHeart Failure rehospitalization30 daysCompare the need for Heart Failure rehospitalization within 30 days.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMIDListed as
40455066DERIVED

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05962255

GET https://conductscience.org/api/trials/v1/NCT05962255/registered