Trial · NCT06014138
Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome
NCT06014138, Phase 2, Phase 3, Recruiting, Guy's and St Thomas' NHS Foundation Trust
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome. Trials, record NCT06014138. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06014138
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome
- NCT number
- NCT06014138
- Status
- Recruiting
- Phases
- Phase 2, Phase 3
- Enrollment
- 20 participants, estimated
- Lead sponsor
- Guy's and St Thomas' NHS Foundation Trust
- Conditions
- Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication, Sedation Complication
- Interventions
- Propofol, Isoflurane
- First posted
- 2023-08-28
- Last updated
- 2026-06-04
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Respiratory drive (P0.1) | 8 hours | Negative pressure in the first 100milliseconds of inspiration (P0.1) - Physiological parameter |
| Secondary | Respiratory effort (Pmus) | 8 hours | End expiratory occlusion pressure (Pmus) - Physiological parameter |
| Secondary | Respiratory effort (PMI) | 8 hours | Pressure Muscle Index (PMI) - Physiological parameter |
| Secondary | Respiratory effort (Oesophageal pressure swings) | 8 hours | Oesophageal pressure swings - Physiological parameter |
| Secondary | Gas exchange (PaO2:FiO2 ratio) | 8 hours | Ratio of arterial partial pressure of oxygen to fractional inspired concentration of oxygen (PaO2:FiO2) - Physiological parameter |
| Secondary | Gas exchange (pulmonary shunt fraction (Qs/Qt)) | 8 hours | Pulmonary shunt fraction (Qs/Qt) - Physiological parameter |
| Secondary | Gas exchange ( ratio of ventilatory 'dead space' to tidal volume (Vd/Vt)) | 8 hours | ratio of ventilatory 'dead space' to tidal volume (Vd/Vt) - Physiological parameter |
| Secondary | Gas exchange (volume of carbon dioxide breathed out (VCO2)) | 8 hours | volume of carbon dioxide breathed out (VCO2) - Physiological parameter |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06014138
GET https://conductscience.org/api/trials/v1/NCT06014138/registered