Trial · NCT06022263
STA363 in the Treatment of Lumbar Disc Herniation
NCT06022263, Phase 1, Completed, Stayble Therapeutics
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. STA363 in the Treatment of Lumbar Disc Herniation. Trials, record NCT06022263. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06022263
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- STA363 in the Treatment of Lumbar Disc Herniation
- NCT number
- NCT06022263
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 25 participants, actual
- Lead sponsor
- Stayble Therapeutics
- Conditions
- Lumbar Disc Herniation
- Interventions
- Lactic Acid, Placebo
- First posted
- 2023-09-01
- Last updated
- 2025-12-10
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Safety and tolerability | Baseline and 1 week and 1,3 and 6 months after intervention for all outcomes except changes in IVD morphology (time frame 1, 3 and 6 months after intervention) | Safety and tolerability will be measured using the following outcomes: * Incidence and nature of adverse events (AEs) * Changes in * physical examination findings * blood pressure and heart rate * 12-lead electrocardiogram * Hematology and clinical chemistry * Pain intensity at the injection site during and 15 minutes after injection (numerical rating scale; NRS). NRS is reported on a 0-10 scale where 0 represents "No pain" and 10 "Worst imaginable pain" * Other aspects of intervertebral disc morphology (IVD) morphology from baseline (e.g., Modic changes) |
| Secondary | Disc volume | Baseline and 1,3 and 6 months after intervention | Volume will be measured by MRI |
| Secondary | Disc height | Baseline and 1,3 and 6 months after intervention | Height will be measured by MRI |
| Secondary | Radicular leg pain | Baseline and 1 week and 1,3 and 6 months after intervention | Leg pain will be reported by the patients using an NRS. (minimum value: 0; maximum value: 10) for 7 consecutive days. Lower scores means a better outcome. |
| Secondary | Patient Global Impression of Change (PGIC) | Baseline and 1 week and 1,3 and 6 months after intervention | PGIC will be reported by the patients using an electronic device |
| Secondary | Disc intensity | Baseline and 1,3 and 6 months after intervention | The intensity of the disc will be measured using T2-weighted MRI |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06022263
GET https://conductscience.org/api/trials/v1/NCT06022263/registered