Trial · NCT06023459
Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR)
NCT06023459, Phase 3, Completed, Yih-Ing Hser
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR). Trials, record NCT06023459. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06023459
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR)
- NCT number
- NCT06023459
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 140 participants, actual
- Lead sponsor
- Yih-Ing Hser
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders, Narcotic-Related Disorders
- Interventions
- Injectable extended-release buprenorphine, Sublingual buprenorphine-naloxone
- First posted
- 2023-09-05
- Last updated
- 2026-04-29
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Comparative effectiveness | Week 2 through Week 14 of the trial | Number of urine drug screen (UDS) results negative for opioids |
| Primary | Feasibility of study implementation | 14 weeks of the trial starting at randomization | The extent to which XR-BUP can be implemented in rural clinic settings, including recruitment, consent, study completion. |
| Primary | Acceptability | 14 weeks of the trial starting at screening | Acceptability of XR-BUP by those implementing or receiving XR-BUP if it is agreeable or satisfaction, percent receiving the first monthly injection, percent receiving at least the first two monthly injection |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 41850520 | DERIVED |
Source PubMed
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| UG1DA049435 | Greater Southern California Node of the Clinical Trials Network | MOONEY, LARISSA JEANETTE; HSER, YIH-ING | UNIVERSITY OF CALIFORNIA LOS ANGELES | NATIONAL INSTITUTE ON DRUG ABUSE | 2019 to 2025 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06023459
GET https://conductscience.org/api/trials/v1/NCT06023459/registered