Trial · NCT06027099
CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial
NCT06027099, Phase 3, Recruiting, Stanford University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial. Trials, record NCT06027099. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06027099
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial
- NCT number
- NCT06027099
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 375 participants, estimated
- Lead sponsor
- Stanford University
- Conditions
- Chronic Pain, Back Pain, Neck Pain, Opioid Misuse
- Interventions
- Tizanidine, MI-Opioid Taper, Placebo, Enhanced Usual Care
- First posted
- 2023-09-07
- Last updated
- 2026-05-06
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time to Baseline Opioid Use | From Postoperative Day 7 through Postoperative Day 365 | Defined as the first of two consecutive reports of return to preoperative daily MME or lower on the modified Brief Pain Inventory (mBPI) or the Recent Opioid Medication Use survey. Preoperative daily MME use is defined as average daily MME assessed during the Preoperative Call in the 1-5 day window prior to surgery. |
| Secondary | Time to Complete Opioid Cessation | From Postoperative Day 7 through Postoperative Day 365 | First of two consecutive reports of opioid cessation on the modified Brief Pain Inventory (mBPI) or the Recent Opioid Medication Use survey. |
| Secondary | Time to Opioid Dispensing Cessation | From Postoperative Day 7 through Postoperative Day 365 | Via state Prescription Drug Monitoring Program (PDMP): First day in the first gap in opioid prescribing ≥ 30 days after surgery |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06027099
GET https://conductscience.org/api/trials/v1/NCT06027099/registered