Trial · NCT06033131
PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia
NCT06033131, Phase 3, Recruiting, Lina Bergman
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia. Trials, record NCT06033131. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06033131
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia
- NCT number
- NCT06033131
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 294 participants, estimated
- Lead sponsor
- Lina Bergman
- Conditions
- Preeclampsia
- Interventions
- Metformin ER, Placebo
- First posted
- 2023-09-13
- Last updated
- 2026-09-28
Source ClinicalTrials.gov
Registered outcomes55
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pregnancy prolongation | From randomisation to delivery, measured in days and hours, up to 105 days | Length of pregnancy from diagnosis of preeclampsia to delivery |
| Secondary | Time for neonatal care | From birth to discharge from neonatal care, measured in days and hours, up to 126 days | Time for neonatal care from birth to discharge |
| Secondary | Neonatal birth weight | At birth | Birth wight measured in grams |
| Other | Occurrence of maternal death | Registered from inclusion to two month post partum | Occurrence of maternal death |
| Other | Occurrence of Eclampsia | Registered from inclusion to two month post partum | Occurrence of Eclampsia |
| Other | Occurrence of Cerebral vascular event | Registered from inclusion to two month post partum | Occurrence of Cerebral vascular event |
| Other | Occurrence of posterior reversible encephalopathy syndrome | Registered from inclusion to two month post partum | Occurrence of posterior reversible encephalopathy syndrome |
| Other | Occurrence of pulmonary edema | Registered from inclusion to two month post partum | Occurrence of pulmonary edema |
| Other | Occurrence of left ventricular failure | Registered from inclusion to two month post partum | Occurrence of left ventricular failure |
| Other | Occurrence of renal dialysis | Registered from inclusion to two month post partum | Occurrence of renal dialysis |
1 to 10 of 55Source ClinicalTrials.gov
See all 55 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers6
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06033131
GET https://conductscience.org/api/trials/v1/NCT06033131/registered?page=2