Trial · NCT06033846
Efficacy and Safety of Adjunctive Minocycline in the Treatment of Autoimmune Encephalitis
NCT06033846, Phase 2, Completed, Xijing Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy and Safety of Adjunctive Minocycline in the Treatment of Autoimmune Encephalitis. Trials, record NCT06033846. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06033846
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy and Safety of Adjunctive Minocycline in the Treatment of Autoimmune Encephalitis
- NCT number
- NCT06033846
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 60 participants, actual
- Lead sponsor
- Xijing Hospital
- Conditions
- Autoimmune Encephalitis
- Interventions
- Minocycline
- First posted
- 2023-09-13
- Last updated
- 2025-08-14
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Montreal-Cognitive Assessment (MoCA)scores | 3 months | the change in MoCA scores from baseline to 3 months |
| Secondary | modified rankin scale (mRS) scores | 1 month | The proportion of patients achieving a ≥1-point or ≥2-point improvement in mRS scores at 1 month |
| Secondary | MoCA scores | from baseline to months 1, 6, and 12 | change in MoCA scores from baseline to months 1, 6, and 12 |
| Secondary | mini-mental state examination (MMSE) scores | from baseline to months 1, 3, 6, and 12 | change in MoCA scores from baseline to months 1, 3, 6, and 12 |
| Secondary | Hamilton anxiety scale (HAMA) scores | from baseline to months 1, 3, 6, and 12 | changes in HAMA scores from baseline to months 1, 3, 6, and 12 |
| Secondary | Hamilton depression scale (HAMD) scores | from baseline to months 1, 3, 6, and 12 | changes in HAMA scores from baseline to months 1, 3, 6, and 12 |
| Other | cerebrospinal fluid (CSF) levels of Soluble Triggering Receptor Expressed on Myeloid cells 2 (sTREM2) | from baseline to months 1, 3, 6, and 12. | the change in CSF levels of sTREM2 levels from baseline to months 1, 3, 6, and 12. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 41902986 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06033846
GET https://conductscience.org/api/trials/v1/NCT06033846/registered