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Trial · NCT06036914

Registered outcomes14

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryUrine Output24 hoursThe total volume of urine produced in milliliters (mL) over 24 hours after initiation of intravenous diuretic.
SecondaryChange in Body WeightBaseline, 24 hoursChange in Body Weight (kg) from Baseline to 24 hours after initiation of intravenous diuretic.
SecondaryChange in NT-proBNPBaseline, 24 hoursChange in NT-proBNP levels (pg/ml) from Baseline to 24 hours after initiation of intravenous diuretic.
SecondaryChange in Urine Sodium ExcretionBaseline, 24 hoursChange in amount of sodium (mmol) excreted in the urine from Baseline to 24 hours after initiation of intravenous diuretic.
SecondaryChange in Apnea-hypopnea IndexBaseline, 24 hours
The apnea-hypopnea index (AHI) is the number of apneas and hypopneas per hour of sleep which is an indicator of severity of sleep apnea AHI will be measured using a Watch Pat or Nox device at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Iohexol Glomerular Filtration Rate (GFR)Baseline, 24 hoursRenal or kidney function was measured by GFR determined by Iohexol clearance. Iohexol GFR will be measured at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Peripheral Vein PressureBaseline, 24 hoursPeripheral vein pressure (mm Hg) will be recorded from existing IV lines through pressure transducer monitoring at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Cardiac OutputBaseline, 24 hoursCardiac output (L/min) is the total volume of blood moved by the heart per minute and will be measured by echocardiography conducted at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Estimated Right Ventricular (RV) Systolic PressureBaseline, 24 hoursEstimated RV systolic pressure (mm Hg) will be measured by echocardiography conducted at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Right Atrial (RA) PressureBaseline, 24 hoursRA pressure (mm Hg) will be measured by echocardiography conducted at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Left Atrial (LA) StrainBaseline, 24 hoursLA strain will be assessed by echocardiography conducted at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Left Ventricular (LV) Global Longitudinal StrainBaseline, 24 hoursLV global longitudinal strain will be assessed by echocardiography conducted at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in Right Ventricular (RV) Global Longitudinal StrainBaseline, 24 hoursRV global longitudinal strain will be assessed by echocardiography conducted at Baseline and 24 hours after initiation of intravenous diuretic.
SecondaryChange in E/e'Baseline, 24 hours
E/e' will be assessed using echocardiography conducted at Baseline and 24 hours after initiation of intravenous diuretic. It is defined as the ratio of peak early diastolic mitral inflow velocity (E) and peak early diastolic mitral annular velocity (e').

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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