Trial · NCT06043830
Managing Opioid Related Sleep Apnea With Acetazolamide
NCT06043830, Phase 2, Completed, University of California, San Diego
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Managing Opioid Related Sleep Apnea With Acetazolamide. Trials, record NCT06043830. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06043830
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Managing Opioid Related Sleep Apnea With Acetazolamide
- NCT number
- NCT06043830
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 39 participants, actual
- Lead sponsor
- University of California, San Diego
- Conditions
- Sleep-Disordered Breathing, Obstructive Sleep Apnea, Central Sleep Apnea, Chronic Pain, Opioid Use
- Interventions
- Acetazolamide, Placebo
- First posted
- 2023-09-21
- Last updated
- 2026-03-10
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Apnea-hypopnea index, NREM Supine | 1 week | The AHI is a measure of sleep apnea severity and is defined as the number of apneas (no breathing for 10+ seconds) and hypopneas (reduced breathing for 10+ seconds associated with a \>=3% desaturation or cortical arousal) per hour of sleep. For the primary outcome, the study will evaluate the AHI during non-rapid eye movement sleep in the supine position. |
| Secondary | Apnea-hypopnea index, Total | 1 week | The AHI is a measure of sleep apnea severity and is defined as the number of apneas (no breathing for 10+ seconds) and hypopneas (reduced breathing for 10+ seconds associated with a \>=3% desaturation or cortical arousal) per hour of sleep. For the primary outcome, the study will evaluate the AHI during sleep in supine and lateral position. |
| Other | Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance | 1 week | Higher scores indicate more symptoms |
| Other | Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Related Impairment | 1 week | Higher scores indicate more symptoms |
| Other | Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Behavior | 1 week | Higher scores indicate more symptoms |
| Other | Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference | 1 week | Higher scores indicate more symptoms |
| Other | 10 minute psychomotor vigilance test | 1 week | Total lapses and mean reaction time |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| K23HL151880 | The Impact of Sleep Disordered Breathing in People who use Opioids | ORR, JEREMY ELLIOT | UNIVERSITY OF CALIFORNIA, SAN DIEGO | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | 2021 to 2025 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as |
|---|---|
| Psychomotor Vigilance Task | Other outcome |
Source ConductCognition
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06043830
GET https://conductscience.org/api/trials/v1/NCT06043830/registered