Trial · NCT06052956
Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses
NCT06052956, Phase 2, Not yet recruiting, University of Rochester
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses. Trials, record NCT06052956. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06052956
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses
- NCT number
- NCT06052956
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 120 participants, estimated
- Lead sponsor
- University of Rochester
- Conditions
- Abscess
- Interventions
Methylene Blue, Lipid Emulsion, Insertion of optical fiber, Laser Illumination (pre-defined dose), Optical Spectroscopy Measurement, Laser Illumination (patient-specific dose), Standard of care abscess drainage
- First posted
- 2023-09-25
- Last updated
- 2026-11-06
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time to removal of the drainage catheter | Day 1 post-intervention until removal of drainage catheter | Drainage catheter output into the drainage bag will be noted daily by a member of the study team and the drainage catheter will be removed when output is reduced to \<5 mL/day, as is standard of care for this patient population. Time to drainage catheter removal (in days) will be recorded for all subjects. |
| Secondary | Mean Change in bacterial burden | Pre and post intervention (approximately 24 hours) | The outcome is reduction in colony-forming units per mL (CFU/mL) of bacteria in aspirate samples collected before and after intervention, measured on a log10 scale. |
| Secondary | Total volume of catheter drainage output | day 14 | Daily output from the placed drainage catheter will be followed from the day of intervention to the either 14 days post-intervention or removal of the drainage catheter, whichever comes first. Daily drainage volume will be recorded, and cumulative drainage volume for the entire catheter placement will be reported. |
| Secondary | mean number of days from intervention to symptom resolution | day 14 | Daily report of fever, chills, pain, heart rate, and blood pressure. The first day on which there is no report of fever, chill, or pain, and where heart rate and blood pressure are within normal ranges for the subject, will be recorded as the date of clinical symptom resolution. The mean number of days from intervention to symptom resolution will be recorded for each arm. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06052956
GET https://conductscience.org/api/trials/v1/NCT06052956/registered