Trial · NCT06072482
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
NCT06072482, Phase 4, Recruiting, Amgen
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis. Trials, record NCT06072482. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06072482
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
- NCT number
- NCT06072482
- Status
- Recruiting
- Phases
- Phase 4
- Enrollment
- 300 participants, estimated
- Lead sponsor
- Amgen
- Conditions
- Antineutrophil Cytoplasmic Antibody-associated Vasculitis
- Interventions
- Avacopan, Placebo, Standard of Care
- First posted
- 2023-10-10
- Last updated
- 2026-09-30
Source ClinicalTrials.gov
Registered outcomes20
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of Participants Experiencing Treatment-emergent Adverse Events (TEAEs) | Up to Month 60 | |
| Primary | Percentage of Participants Experiencing Adverse Events of Special Interest | Up to Month 60 | |
| Primary | Percentage of Participants Experiencing Serious Adverse Events | Up to Month 60 | |
| Primary | Percentage of Participants Experiencing Adverse Events Leading to Withdrawal | Up to Month 60 | |
| Primary | Percentage of Participants Experiencing Adverse Events Leading to Death | Up to Month 60 | |
| Primary | Number of Participants Experiencing Clinical Significant Changes from Baseline in Vital Signs Measurements | Up to Month 60 | |
| Primary | Number of Participants Experiencing Clinical Significant Changes from Baseline in Hematology Assessments | Up to Month 60 | |
| Primary | Number of Participants Experiencing Clinical Significant Changes from Baseline in Serum Chemistry Assessments | Up to Month 60 | |
| Primary | Number of Participants Experiencing Clinical Significant Changes from Baseline in Urinalysis Assessments | Up to Month 60 | |
| Secondary | Group A and B Participants who Achieved Remission at Month 12: Time to Relapse in AAV Between Month 12 and Month 60 | Month 12 to Month 60 |
1 to 10 of 20Source ClinicalTrials.gov
See all 20 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06072482
GET https://conductscience.org/api/trials/v1/NCT06072482/registered